N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate

In the crystal structure of the title compound, C(18)H(17)FN(4)O(2)S·2H(2)O, the organic mol­ecules are linked by inter­molecular O—H⋯O, O—H⋯N and N—H⋯O hydrogen bonds with the water mol­ecules, generating a three-dimensional network. The imidazole ring system forms a dihedral angle of 24.9 (2)° wit...

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Detalles Bibliográficos
Autores principales: Bühler, Stefanie, Schollmeyer, Dieter, Hauser, Dominik, Albrecht, Wolfgang, Laufer, Stefan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980079/
https://www.ncbi.nlm.nih.gov/pubmed/21580011
http://dx.doi.org/10.1107/S1600536809051873
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author Bühler, Stefanie
Schollmeyer, Dieter
Hauser, Dominik
Albrecht, Wolfgang
Laufer, Stefan
author_facet Bühler, Stefanie
Schollmeyer, Dieter
Hauser, Dominik
Albrecht, Wolfgang
Laufer, Stefan
author_sort Bühler, Stefanie
collection PubMed
description In the crystal structure of the title compound, C(18)H(17)FN(4)O(2)S·2H(2)O, the organic mol­ecules are linked by inter­molecular O—H⋯O, O—H⋯N and N—H⋯O hydrogen bonds with the water mol­ecules, generating a three-dimensional network. The imidazole ring system forms a dihedral angle of 24.9 (2)° with the 4-fluoro­phenyl ring. The pyridine ring is oriented approximately perpendicular [72.24 (8)°] to the imidazole ring system.
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spelling pubmed-29800792010-12-30 N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate Bühler, Stefanie Schollmeyer, Dieter Hauser, Dominik Albrecht, Wolfgang Laufer, Stefan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the crystal structure of the title compound, C(18)H(17)FN(4)O(2)S·2H(2)O, the organic mol­ecules are linked by inter­molecular O—H⋯O, O—H⋯N and N—H⋯O hydrogen bonds with the water mol­ecules, generating a three-dimensional network. The imidazole ring system forms a dihedral angle of 24.9 (2)° with the 4-fluoro­phenyl ring. The pyridine ring is oriented approximately perpendicular [72.24 (8)°] to the imidazole ring system. International Union of Crystallography 2009-12-12 /pmc/articles/PMC2980079/ /pubmed/21580011 http://dx.doi.org/10.1107/S1600536809051873 Text en © Bühler et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Bühler, Stefanie
Schollmeyer, Dieter
Hauser, Dominik
Albrecht, Wolfgang
Laufer, Stefan
N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate
title N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate
title_full N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate
title_fullStr N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate
title_full_unstemmed N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate
title_short N-{4-[4-(4-Fluoro­phen­yl)-1-methyl-2-[(R)-methyl­sulfin­yl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate
title_sort n-{4-[4-(4-fluoro­phen­yl)-1-methyl-2-[(r)-methyl­sulfin­yl]-1h-imidazol-5-yl]-2-pyridyl}acetamide dihydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980079/
https://www.ncbi.nlm.nih.gov/pubmed/21580011
http://dx.doi.org/10.1107/S1600536809051873
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