3,4,5-Trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)

The title compound, 2C(16)H(13)N(3)O(4)·C(18)H(14)N(4)·2CH(4)O, was crystallized from the reaction between 3,4,5-trihydroxy­benzoyl­hydrazine and indole-2-carbaldehyde in a mixture of ethanol and methanol. The compound is a stoichiometric 2:1 cocrystal of the methanol-solvated reaction product, 3,4,...

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Autores principales: Khaledi, Hamid, Alhadi, Abeer A., Mohd Ali, Hapipah, Robinson, Ward T., Abdulla, Mahmood A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980105/
https://www.ncbi.nlm.nih.gov/pubmed/21579996
http://dx.doi.org/10.1107/S1600536809052465
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author Khaledi, Hamid
Alhadi, Abeer A.
Mohd Ali, Hapipah
Robinson, Ward T.
Abdulla, Mahmood A.
author_facet Khaledi, Hamid
Alhadi, Abeer A.
Mohd Ali, Hapipah
Robinson, Ward T.
Abdulla, Mahmood A.
author_sort Khaledi, Hamid
collection PubMed
description The title compound, 2C(16)H(13)N(3)O(4)·C(18)H(14)N(4)·2CH(4)O, was crystallized from the reaction between 3,4,5-trihydroxy­benzoyl­hydrazine and indole-2-carbaldehyde in a mixture of ethanol and methanol. The compound is a stoichiometric 2:1 cocrystal of the methanol-solvated reaction product, 3,4,5-trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide and 1H-indole-2-carbaldehyde azine that arose unexpectedly during the synthesis. The former mol­ecules are linked by O—H⋯O hydrogen bonds and also by π–π stacking inter­actions between benzoyl­hydrazide rings into a two-dimensional network. The methanol solvent mol­ecules are hydrogen bonded to this network. The centrosymmetric azine mol­ecules are not engaged in hydrogen bonding.
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spelling pubmed-29801052010-12-30 3,4,5-Trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2) Khaledi, Hamid Alhadi, Abeer A. Mohd Ali, Hapipah Robinson, Ward T. Abdulla, Mahmood A. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, 2C(16)H(13)N(3)O(4)·C(18)H(14)N(4)·2CH(4)O, was crystallized from the reaction between 3,4,5-trihydroxy­benzoyl­hydrazine and indole-2-carbaldehyde in a mixture of ethanol and methanol. The compound is a stoichiometric 2:1 cocrystal of the methanol-solvated reaction product, 3,4,5-trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide and 1H-indole-2-carbaldehyde azine that arose unexpectedly during the synthesis. The former mol­ecules are linked by O—H⋯O hydrogen bonds and also by π–π stacking inter­actions between benzoyl­hydrazide rings into a two-dimensional network. The methanol solvent mol­ecules are hydrogen bonded to this network. The centrosymmetric azine mol­ecules are not engaged in hydrogen bonding. International Union of Crystallography 2009-12-12 /pmc/articles/PMC2980105/ /pubmed/21579996 http://dx.doi.org/10.1107/S1600536809052465 Text en © Khaledi et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Khaledi, Hamid
Alhadi, Abeer A.
Mohd Ali, Hapipah
Robinson, Ward T.
Abdulla, Mahmood A.
3,4,5-Trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)
title 3,4,5-Trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)
title_full 3,4,5-Trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)
title_fullStr 3,4,5-Trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)
title_full_unstemmed 3,4,5-Trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)
title_short 3,4,5-Trihydr­oxy-N′-(1H-indol-2-ylmethyl­idene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)
title_sort 3,4,5-trihydr­oxy-n′-(1h-indol-2-ylmethyl­idene)benzohydrazide–1h-indole-2-carbaldehyde azine–methanol (2/1/2)
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980105/
https://www.ncbi.nlm.nih.gov/pubmed/21579996
http://dx.doi.org/10.1107/S1600536809052465
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