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Gabapentin-lactum–chloranilic acid (1/1)
In the title compound, C(9)H(15)NO·C(6)H(2)Cl(2)O(4) [sytematic name: 2-azaspiro[4.5]decan-3-one–chloranilic acid (1/1)], the cyclohexane ring of the lactam molecule adopts a slightly distorted normal chair conformation and the five-membered 3-azaspiro ring is in a slightly distorted chair confo...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980187/ https://www.ncbi.nlm.nih.gov/pubmed/21580051 http://dx.doi.org/10.1107/S1600536809053410 |
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author | Jasinski, Jerry P. Butcher, Ray J. Hakim Al-arique, Q. N. M. Yathirajan, H. S. Narayana, B. |
author_facet | Jasinski, Jerry P. Butcher, Ray J. Hakim Al-arique, Q. N. M. Yathirajan, H. S. Narayana, B. |
author_sort | Jasinski, Jerry P. |
collection | PubMed |
description | In the title compound, C(9)H(15)NO·C(6)H(2)Cl(2)O(4) [sytematic name: 2-azaspiro[4.5]decan-3-one–chloranilic acid (1/1)], the cyclohexane ring of the lactam molecule adopts a slightly distorted normal chair conformation and the five-membered 3-azaspiro ring is in a slightly distorted chair conformation. The dihedral angle between the least-squares planes of the cyclohexane and 3-azaspiro rings is 84.0 (3)°. In the crystal, the chloranilic acid molecule and the gabapentin-lactum molecules are held together by strong intermolecular N—H⋯O and O—H⋯O hydrogen bonds with two bifurcated O acceptor atoms on the chloranilic acid molecule and one on the gabapentin-lactum molecule, each bonding with an inter- and intramolecular hydrogen bond. The molecules are linked into chains parallel to (011) and propagating along the b axis. |
format | Text |
id | pubmed-2980187 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29801872010-12-30 Gabapentin-lactum–chloranilic acid (1/1) Jasinski, Jerry P. Butcher, Ray J. Hakim Al-arique, Q. N. M. Yathirajan, H. S. Narayana, B. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(9)H(15)NO·C(6)H(2)Cl(2)O(4) [sytematic name: 2-azaspiro[4.5]decan-3-one–chloranilic acid (1/1)], the cyclohexane ring of the lactam molecule adopts a slightly distorted normal chair conformation and the five-membered 3-azaspiro ring is in a slightly distorted chair conformation. The dihedral angle between the least-squares planes of the cyclohexane and 3-azaspiro rings is 84.0 (3)°. In the crystal, the chloranilic acid molecule and the gabapentin-lactum molecules are held together by strong intermolecular N—H⋯O and O—H⋯O hydrogen bonds with two bifurcated O acceptor atoms on the chloranilic acid molecule and one on the gabapentin-lactum molecule, each bonding with an inter- and intramolecular hydrogen bond. The molecules are linked into chains parallel to (011) and propagating along the b axis. International Union of Crystallography 2009-12-16 /pmc/articles/PMC2980187/ /pubmed/21580051 http://dx.doi.org/10.1107/S1600536809053410 Text en © Jasinski et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Jasinski, Jerry P. Butcher, Ray J. Hakim Al-arique, Q. N. M. Yathirajan, H. S. Narayana, B. Gabapentin-lactum–chloranilic acid (1/1) |
title | Gabapentin-lactum–chloranilic acid (1/1) |
title_full | Gabapentin-lactum–chloranilic acid (1/1) |
title_fullStr | Gabapentin-lactum–chloranilic acid (1/1) |
title_full_unstemmed | Gabapentin-lactum–chloranilic acid (1/1) |
title_short | Gabapentin-lactum–chloranilic acid (1/1) |
title_sort | gabapentin-lactum–chloranilic acid (1/1) |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980187/ https://www.ncbi.nlm.nih.gov/pubmed/21580051 http://dx.doi.org/10.1107/S1600536809053410 |
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