Cargando…

Gabapentin-lactum–chloranilic acid (1/1)

In the title compound, C(9)H(15)NO·C(6)H(2)Cl(2)O(4) [sytematic name: 2-aza­spiro­[4.5]decan-3-one–chloranilic acid (1/1)], the cyclo­hexane ring of the lactam molecule adopts a slightly distorted normal chair conformation and the five-membered 3-aza­spiro ring is in a slightly distorted chair confo...

Descripción completa

Detalles Bibliográficos
Autores principales: Jasinski, Jerry P., Butcher, Ray J., Hakim Al-arique, Q. N. M., Yathirajan, H. S., Narayana, B.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980187/
https://www.ncbi.nlm.nih.gov/pubmed/21580051
http://dx.doi.org/10.1107/S1600536809053410
_version_ 1782191598523645952
author Jasinski, Jerry P.
Butcher, Ray J.
Hakim Al-arique, Q. N. M.
Yathirajan, H. S.
Narayana, B.
author_facet Jasinski, Jerry P.
Butcher, Ray J.
Hakim Al-arique, Q. N. M.
Yathirajan, H. S.
Narayana, B.
author_sort Jasinski, Jerry P.
collection PubMed
description In the title compound, C(9)H(15)NO·C(6)H(2)Cl(2)O(4) [sytematic name: 2-aza­spiro­[4.5]decan-3-one–chloranilic acid (1/1)], the cyclo­hexane ring of the lactam molecule adopts a slightly distorted normal chair conformation and the five-membered 3-aza­spiro ring is in a slightly distorted chair conformation. The dihedral angle between the least-squares planes of the cyclohexane and 3-azaspiro rings is 84.0 (3)°. In the crystal, the chloranilic acid mol­ecule and the gabapentin-lactum mol­ecules are held together by strong inter­molecular N—H⋯O and O—H⋯O hydrogen bonds with two bifurcated O acceptor atoms on the chloranilic acid mol­ecule and one on the gabapentin-lactum mol­ecule, each bonding with an inter- and intra­molecular hydrogen bond. The molecules are linked into chains parallel to (011) and propagating along the b axis.
format Text
id pubmed-2980187
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29801872010-12-30 Gabapentin-lactum–chloranilic acid (1/1) Jasinski, Jerry P. Butcher, Ray J. Hakim Al-arique, Q. N. M. Yathirajan, H. S. Narayana, B. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(9)H(15)NO·C(6)H(2)Cl(2)O(4) [sytematic name: 2-aza­spiro­[4.5]decan-3-one–chloranilic acid (1/1)], the cyclo­hexane ring of the lactam molecule adopts a slightly distorted normal chair conformation and the five-membered 3-aza­spiro ring is in a slightly distorted chair conformation. The dihedral angle between the least-squares planes of the cyclohexane and 3-azaspiro rings is 84.0 (3)°. In the crystal, the chloranilic acid mol­ecule and the gabapentin-lactum mol­ecules are held together by strong inter­molecular N—H⋯O and O—H⋯O hydrogen bonds with two bifurcated O acceptor atoms on the chloranilic acid mol­ecule and one on the gabapentin-lactum mol­ecule, each bonding with an inter- and intra­molecular hydrogen bond. The molecules are linked into chains parallel to (011) and propagating along the b axis. International Union of Crystallography 2009-12-16 /pmc/articles/PMC2980187/ /pubmed/21580051 http://dx.doi.org/10.1107/S1600536809053410 Text en © Jasinski et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Jasinski, Jerry P.
Butcher, Ray J.
Hakim Al-arique, Q. N. M.
Yathirajan, H. S.
Narayana, B.
Gabapentin-lactum–chloranilic acid (1/1)
title Gabapentin-lactum–chloranilic acid (1/1)
title_full Gabapentin-lactum–chloranilic acid (1/1)
title_fullStr Gabapentin-lactum–chloranilic acid (1/1)
title_full_unstemmed Gabapentin-lactum–chloranilic acid (1/1)
title_short Gabapentin-lactum–chloranilic acid (1/1)
title_sort gabapentin-lactum–chloranilic acid (1/1)
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980187/
https://www.ncbi.nlm.nih.gov/pubmed/21580051
http://dx.doi.org/10.1107/S1600536809053410
work_keys_str_mv AT jasinskijerryp gabapentinlactumchloranilicacid11
AT butcherrayj gabapentinlactumchloranilicacid11
AT hakimalariqueqnm gabapentinlactumchloranilicacid11
AT yathirajanhs gabapentinlactumchloranilicacid11
AT narayanab gabapentinlactumchloranilicacid11