Sox2 Is Essential for Formation of Trophectoderm in the Preimplantation Embryo

BACKGROUND: In preimplantation mammalian development the transcription factor Sox2 (SRY-related HMG-box gene 2) forms a complex with Oct4 and functions in maintenance of self-renewal of the pluripotent inner cell mass (ICM). Previously it was shown that Sox2−/− embryos die soon after implantation. H...

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Detalles Bibliográficos
Autores principales: Keramari, Maria, Razavi, Janet, Ingman, Karen A., Patsch, Christoph, Edenhofer, Frank, Ward, Christopher M., Kimber, Susan J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980489/
https://www.ncbi.nlm.nih.gov/pubmed/21103067
http://dx.doi.org/10.1371/journal.pone.0013952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980489/
https://www.ncbi.nlm.nih.gov/pubmed/21103067
http://dx.doi.org/10.1371/journal.pone.0013952

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