Comparative evaluation of microleakage of fifth, sixth, and seventh generation dentin bonding agents: An in vitro study

OBJECTIVES: The purpose of this study was to determine the microleakage in the 5(th) and 6(th) generation bonding agents with that compared with the newly introduced 7(th) generation bonding agents using three bonding agents. MATERIALS AND METHODS: A total of 50 recently extracted human upper premolars were subjected to the study. Class V cavity preparations were prepared on the buccal and lingual surfaces of the extracted premolars with occlusal margins in the enamel and gingival margins in the cementum/dentin. The teeth were divided into five groups of 10 teeth each and 20 cavity preparations per group. In the experimental groups, cavities were treated with Single-Bond, Adper Prompt, i-Bond, Clearfil S3, and G-Bond as the dentin bonding agents. After the application of the dentin bonding agents, the cavity preparations were restored with resin composite (Clearfil APX). The specimens were thermocycled, stained with methylene blue dye, and sectioned to evaluate the dye penetration. Data were analyzed using the one-way ANOVA test (Kruskal–Wallis) and Dunn’s procedure for pairwise comparison of the data. RESULTS: This study showed that at the coronal margin and the apical margins, the preparations treated with Clearfil S3 showed significantly less leakage than the other groups. Enamel margins provided better marginal sealing than dentin/ cementum margins. INTERPRETATION AND CONCLUSION: The study demonstrated that Clearfil S3 bond had a better sealing ability at both coronal (enamel) and apical (dentin/cementum) margins compared with the other dentin bonding agents used.