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Viral Factors Induce Hedgehog Pathway Activation in Humans with Viral Hepatitis, Cirrhosis, and Hepatocellular Carcinoma
Hh pathway activation promotes many processes that occur during fibrogenic liver repair. Whether the Hh pathway modulates the outcomes of virally-mediated liver injury has never been examined. Gene-profiling studies of human hepatocellular carcinomas (HCC) demonstrate Hh pathway activation in HCCs r...
Autores principales: | Pereira, Thiago de Almeida, Witek, Rafal P., Syn, Wing-Kin, Choi, Steve S., Bradrick, Shelton, Karaca, Gamze F, Agboola, Kolade M., Jung, Youngmi, Omenetti, Alessia, Moylan, Cynthia A., Yang, Liu, Fernandez-Zapico, Martin E., Jhaveri, Ravi, Shah, Vijay H., Pereira, Fausto E., Diehl, Anna Mae |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980808/ https://www.ncbi.nlm.nih.gov/pubmed/20697376 http://dx.doi.org/10.1038/labinvest.2010.147 |
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