ACTH AND THE DEXAMETHASONE SUPPRESSION TEST IN DEPRESSION

Hypercortisolemia, as measured by baseline serum Cortisol levels (Carroll and Mendels, 1976) and abnormal response to dexamethasone suppression test (DST) (Carroll et at., 1981) is thought to characterize abnormal hypothalamic-pituitory- adrenal (HPA) axis functions in patients of depression. Whethe...

Descripción completa

Detalles Bibliográficos
Autores principales: Jainer, Ashok Kumar, Sharma, Mukul, Trivedt, J.K., Agarwal, C.G., Tiwari, S.C.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1992
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980985/
https://www.ncbi.nlm.nih.gov/pubmed/21776099
Descripción
Sumario:Hypercortisolemia, as measured by baseline serum Cortisol levels (Carroll and Mendels, 1976) and abnormal response to dexamethasone suppression test (DST) (Carroll et at., 1981) is thought to characterize abnormal hypothalamic-pituitory- adrenal (HPA) axis functions in patients of depression. Whether adrenocorticotrophic hormone (ACTH) shows similar abnormalities is a matter of controversy. Whereas Nasretal. (1983) and Roy et al. (1986) reported higher plasme ACTH levels in depressed patients as compared to controls. Fang et al. (1981) and Yerevanian and Woolf (1933) did not find such difference.

Ejemplares similares