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The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab
Objective. SSc is an autoimmune disease characterized by fibrosis of the skin and internal organs. Although the aetiology remains uncertain, many reports have suggested that IL-6 is involved in SSc pathogenesis. Tocilizumab, an anti-IL-6 receptor antibody, is an anti-arthritis medicine that works th...
Autores principales: | Shima, Yoshihito, Kuwahara, Yusuke, Murota, Hiroyuki, Kitaba, Shun, Kawai, Mari, Hirano, Toru, Arimitsu, Junsuke, Narazaki, Masashi, Hagihara, Keisuke, Ogata, Atsushi, Katayama, Ichiro, Kawase, Ichiro, Kishimoto, Tadamitsu, Tanaka, Toshio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981510/ https://www.ncbi.nlm.nih.gov/pubmed/20819796 http://dx.doi.org/10.1093/rheumatology/keq275 |
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