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Analysis of Mice Lacking DNaseI Hypersensitive Sites at the 5′ End of the IgH Locus

The 5′ end of the IgH locus contains a cluster of DNaseI hypersensitive sites, one of which (HS1) was shown to be pro-B cell specific and to contain binding sites for the transcription factors PU.1, E2A, and Pax5. These data as well as the location of the hypersensitive sites at the 5′ border of the...

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Detalles Bibliográficos
Autores principales: Perlot, Thomas, Pawlitzky, Inka, Manis, John P., Zarrin, Ali A., Brodeur, Peter H., Alt, Frederick W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981565/
https://www.ncbi.nlm.nih.gov/pubmed/21085586
http://dx.doi.org/10.1371/journal.pone.0013992