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Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis

The selection and soaring spread of Mycobacterium tuberculosis multidrug-resistant (MDR-TB) and extensively drug-resistant strains (XDR-TB) is a severe public health problem. Currently, there is an urgent need for new drugs for tuberculosis treatment, with novel mechanisms of action and, moreover, t...

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Detalles Bibliográficos
Autores principales:	Lucarelli, Anna P., Buroni, Silvia, Pasca, Maria R., Rizzi, Menico, Cavagnino, Andrea, Valentini, Giovanna, Riccardi, Giovanna, Chiarelli, Laurent R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981568/ https://www.ncbi.nlm.nih.gov/pubmed/21085589 http://dx.doi.org/10.1371/journal.pone.0015494

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