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The D299G/T399I Toll-Like Receptor 4 Variant Associates with Body and Liver Fat: Results from the TULIP and METSIM Studies

BACKGROUND: Toll-like-receptor 4 (TLR) is discussed to provide a molecular link between obesity, inflammation and insulin resistance. Genetic studies with replications in non-diabetic individuals in regard to their fat distribution or insulin resistance according to their carrier status of a common...

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Detalles Bibliográficos
Autores principales: Weyrich, Peter, Staiger, Harald, Stančáková, Alena, Machicao, Fausto, Machann, Jürgen, Schick, Fritz, Stefan, Norbert, Kuusisto, Johanna, Laakso, Markku, Schäfer, Silke, Fritsche, Andreas, Häring, Hans-Ulrich
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981584/
https://www.ncbi.nlm.nih.gov/pubmed/21125016
http://dx.doi.org/10.1371/journal.pone.0013980