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Plasmid injection and application of electric pulses alter endogenous mRNA and protein expression in B16.F10 mouse melanomas
The application of electric pulses to tissues causes cell membrane destabilization, allowing exogenous molecules to enter the cells. This delivery technique can be used for plasmid gene therapy. Reporter gene expression after plasmid delivery with eight representative published protocols was compare...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981654/ https://www.ncbi.nlm.nih.gov/pubmed/20706286 http://dx.doi.org/10.1038/cgt.2010.43 |