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Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles
A simple and efficient synthesis of novel 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles, utilizing sodium ethoxide as a catalyst via a Friedländer condensation reaction between 3-acetyl-9-ethyl-9H-carbazole or 3,6-diacetyl-9-ethyl-9H-carbazole and β-aminoaldehydes or β-aminoketones is...
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Formato: | Texto |
Lenguaje: | English |
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Beilstein-Institut
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981831/ https://www.ncbi.nlm.nih.gov/pubmed/21085511 http://dx.doi.org/10.3762/bjoc.6.108 |
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author | Li, Yang Gao, Wentao |
author_facet | Li, Yang Gao, Wentao |
author_sort | Li, Yang |
collection | PubMed |
description | A simple and efficient synthesis of novel 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles, utilizing sodium ethoxide as a catalyst via a Friedländer condensation reaction between 3-acetyl-9-ethyl-9H-carbazole or 3,6-diacetyl-9-ethyl-9H-carbazole and β-aminoaldehydes or β-aminoketones is described. All of the title compounds were obtained in good yields of 52–72% and their structures were confirmed by IR, (1)H NMR, MS, and elemental analysis. |
format | Text |
id | pubmed-2981831 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-29818312010-11-17 Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles Li, Yang Gao, Wentao Beilstein J Org Chem Full Research Paper A simple and efficient synthesis of novel 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles, utilizing sodium ethoxide as a catalyst via a Friedländer condensation reaction between 3-acetyl-9-ethyl-9H-carbazole or 3,6-diacetyl-9-ethyl-9H-carbazole and β-aminoaldehydes or β-aminoketones is described. All of the title compounds were obtained in good yields of 52–72% and their structures were confirmed by IR, (1)H NMR, MS, and elemental analysis. Beilstein-Institut 2010-10-08 /pmc/articles/PMC2981831/ /pubmed/21085511 http://dx.doi.org/10.3762/bjoc.6.108 Text en Copyright © 2010, Li and Gao https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
spellingShingle | Full Research Paper Li, Yang Gao, Wentao Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles |
title | Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles |
title_full | Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles |
title_fullStr | Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles |
title_full_unstemmed | Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles |
title_short | Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles |
title_sort | synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9h-carbazoles |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981831/ https://www.ncbi.nlm.nih.gov/pubmed/21085511 http://dx.doi.org/10.3762/bjoc.6.108 |
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