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CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT

Efficacy of centpropazine, a new antidepressant, has been evaluated in forty two patients of endogenous depression. The 4 week open trial was carried out in a dose-range of 40 to 120mg per day. A significant lowering of Hamilton Depression Rating Scale (HDRS) score was observed in 34 patient. The an...

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Autores principales: Srivastava, J.S., Gupta, P.P., Asthana, O.P., Nityanand, S., Devi, S., Doongaji, D.R., Sethi, B.B., Singh, Gurmeet, Srimal, R.C., Dhawan, B.N.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982079/
https://www.ncbi.nlm.nih.gov/pubmed/21776129
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author Srivastava, J.S.
Gupta, P.P.
Asthana, O.P.
Nityanand, S.
Devi, S.
Doongaji, D.R.
Sethi, B.B.
Singh, Gurmeet
Srimal, R.C.
Dhawan, B.N.
author_facet Srivastava, J.S.
Gupta, P.P.
Asthana, O.P.
Nityanand, S.
Devi, S.
Doongaji, D.R.
Sethi, B.B.
Singh, Gurmeet
Srimal, R.C.
Dhawan, B.N.
author_sort Srivastava, J.S.
collection PubMed
description Efficacy of centpropazine, a new antidepressant, has been evaluated in forty two patients of endogenous depression. The 4 week open trial was carried out in a dose-range of 40 to 120mg per day. A significant lowering of Hamilton Depression Rating Scale (HDRS) score was observed in 34 patient. The antidepressant effect could be detected in 9 patients within one week, in 28 cases in two weeks and in all the 34 patients by third week. Giddiness, headache, dryness of mouth and weakness were reported by 11 patients.
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spelling pubmed-29820792011-07-20 CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT Srivastava, J.S. Gupta, P.P. Asthana, O.P. Nityanand, S. Devi, S. Doongaji, D.R. Sethi, B.B. Singh, Gurmeet Srimal, R.C. Dhawan, B.N. Indian J Psychiatry Original Article Efficacy of centpropazine, a new antidepressant, has been evaluated in forty two patients of endogenous depression. The 4 week open trial was carried out in a dose-range of 40 to 120mg per day. A significant lowering of Hamilton Depression Rating Scale (HDRS) score was observed in 34 patient. The antidepressant effect could be detected in 9 patients within one week, in 28 cases in two weeks and in all the 34 patients by third week. Giddiness, headache, dryness of mouth and weakness were reported by 11 patients. Medknow Publications 1992 /pmc/articles/PMC2982079/ /pubmed/21776129 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Srivastava, J.S.
Gupta, P.P.
Asthana, O.P.
Nityanand, S.
Devi, S.
Doongaji, D.R.
Sethi, B.B.
Singh, Gurmeet
Srimal, R.C.
Dhawan, B.N.
CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT
title CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT
title_full CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT
title_fullStr CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT
title_full_unstemmed CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT
title_short CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT
title_sort clinical efficacy of centporpazine-a new antidepressant
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982079/
https://www.ncbi.nlm.nih.gov/pubmed/21776129
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