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CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT
Efficacy of centpropazine, a new antidepressant, has been evaluated in forty two patients of endogenous depression. The 4 week open trial was carried out in a dose-range of 40 to 120mg per day. A significant lowering of Hamilton Depression Rating Scale (HDRS) score was observed in 34 patient. The an...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982079/ https://www.ncbi.nlm.nih.gov/pubmed/21776129 |
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author | Srivastava, J.S. Gupta, P.P. Asthana, O.P. Nityanand, S. Devi, S. Doongaji, D.R. Sethi, B.B. Singh, Gurmeet Srimal, R.C. Dhawan, B.N. |
author_facet | Srivastava, J.S. Gupta, P.P. Asthana, O.P. Nityanand, S. Devi, S. Doongaji, D.R. Sethi, B.B. Singh, Gurmeet Srimal, R.C. Dhawan, B.N. |
author_sort | Srivastava, J.S. |
collection | PubMed |
description | Efficacy of centpropazine, a new antidepressant, has been evaluated in forty two patients of endogenous depression. The 4 week open trial was carried out in a dose-range of 40 to 120mg per day. A significant lowering of Hamilton Depression Rating Scale (HDRS) score was observed in 34 patient. The antidepressant effect could be detected in 9 patients within one week, in 28 cases in two weeks and in all the 34 patients by third week. Giddiness, headache, dryness of mouth and weakness were reported by 11 patients. |
format | Text |
id | pubmed-2982079 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1992 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-29820792011-07-20 CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT Srivastava, J.S. Gupta, P.P. Asthana, O.P. Nityanand, S. Devi, S. Doongaji, D.R. Sethi, B.B. Singh, Gurmeet Srimal, R.C. Dhawan, B.N. Indian J Psychiatry Original Article Efficacy of centpropazine, a new antidepressant, has been evaluated in forty two patients of endogenous depression. The 4 week open trial was carried out in a dose-range of 40 to 120mg per day. A significant lowering of Hamilton Depression Rating Scale (HDRS) score was observed in 34 patient. The antidepressant effect could be detected in 9 patients within one week, in 28 cases in two weeks and in all the 34 patients by third week. Giddiness, headache, dryness of mouth and weakness were reported by 11 patients. Medknow Publications 1992 /pmc/articles/PMC2982079/ /pubmed/21776129 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Srivastava, J.S. Gupta, P.P. Asthana, O.P. Nityanand, S. Devi, S. Doongaji, D.R. Sethi, B.B. Singh, Gurmeet Srimal, R.C. Dhawan, B.N. CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT |
title | CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT |
title_full | CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT |
title_fullStr | CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT |
title_full_unstemmed | CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT |
title_short | CLINICAL EFFICACY OF CENTPORPAZINE-A NEW ANTIDEPRESSANT |
title_sort | clinical efficacy of centporpazine-a new antidepressant |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982079/ https://www.ncbi.nlm.nih.gov/pubmed/21776129 |
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