High density lipoproteins-based therapies for cardiovascular disease

Atherosclerosis is the leading cause of death in developed countries. High density lipoproteins (HDL) cholesterol level correlates inversely with the risk of cardiovascular diseases. Thus, HDL has obtained lots of interest for drug development. In this review, we summarized the mechanisms for the an...

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Detalles Bibliográficos
Autores principales: Gao, Xuan, Yuan, Shujun
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982209/
https://www.ncbi.nlm.nih.gov/pubmed/21187875
http://dx.doi.org/10.4103/0975-3583.70898
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author Gao, Xuan
Yuan, Shujun
author_facet Gao, Xuan
Yuan, Shujun
author_sort Gao, Xuan
collection PubMed
description Atherosclerosis is the leading cause of death in developed countries. High density lipoproteins (HDL) cholesterol level correlates inversely with the risk of cardiovascular diseases. Thus, HDL has obtained lots of interest for drug development. In this review, we summarized the mechanisms for the antiatherogenic function of HDL, current HDL-based drugs in clinical use and the future direction for HDL-based therapy development.
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spelling pubmed-29822092010-12-23 High density lipoproteins-based therapies for cardiovascular disease Gao, Xuan Yuan, Shujun J Cardiovasc Dis Res Invited Review Atherosclerosis is the leading cause of death in developed countries. High density lipoproteins (HDL) cholesterol level correlates inversely with the risk of cardiovascular diseases. Thus, HDL has obtained lots of interest for drug development. In this review, we summarized the mechanisms for the antiatherogenic function of HDL, current HDL-based drugs in clinical use and the future direction for HDL-based therapy development. Medknow Publications 2010 /pmc/articles/PMC2982209/ /pubmed/21187875 http://dx.doi.org/10.4103/0975-3583.70898 Text en © Journal of Cardiovascular Disease Research http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Invited Review
Gao, Xuan
Yuan, Shujun
High density lipoproteins-based therapies for cardiovascular disease
title High density lipoproteins-based therapies for cardiovascular disease
title_full High density lipoproteins-based therapies for cardiovascular disease
title_fullStr High density lipoproteins-based therapies for cardiovascular disease
title_full_unstemmed High density lipoproteins-based therapies for cardiovascular disease
title_short High density lipoproteins-based therapies for cardiovascular disease
title_sort high density lipoproteins-based therapies for cardiovascular disease
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982209/
https://www.ncbi.nlm.nih.gov/pubmed/21187875
http://dx.doi.org/10.4103/0975-3583.70898
work_keys_str_mv AT gaoxuan highdensitylipoproteinsbasedtherapiesforcardiovasculardisease
AT yuanshujun highdensitylipoproteinsbasedtherapiesforcardiovasculardisease

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