Cargando…

Silencing of PTK7 in Colon Cancer Cells: Caspase-10-Dependent Apoptosis via Mitochondrial Pathway

Protein tyrosine kinase-7 (PTK7) is a catalytically inactive receptor tyrosine kinase (RTK). PTK7 is upregulated in many common human cancers, including colon cancer, lung cancer, gastric cancer and acute myeloid leukemia. The reason for this up-regulation is not yet known. To explore the functional...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Ling, Sefah, Kwame, O'Donoghue, Meghan B., Zhu, Guizhi, Shangguan, Dihua, Noorali, Afshan, Chen, Yan, Zhou, Lei, Tan, Weihong
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982840/ https://www.ncbi.nlm.nih.gov/pubmed/21103379 http://dx.doi.org/10.1371/journal.pone.0014018

Ejemplares similares

Molecular recognition of acute myeloid leukemia using aptamers
por: Sefah, Kwame, et al.
Publicado: (2009)

Lovastatin exerts protective effects on endothelial cells via upregulation of PTK2B
por: Chu, Weiwei, et al.
Publicado: (2016)

A Synthetic Aptamer-Drug Adduct for Targeted Liver Cancer Therapy
por: Trinh, Thu Le, et al.
Publicado: (2015)

Isolation of Human Colon Stem Cells Using Surface Expression of PTK7
por: Jung, Peter, et al.
Publicado: (2015)

Anti-PTK7 Monoclonal Antibodies Inhibit Angiogenesis by Suppressing PTK7 Function
por: Oh, Si Won, et al.
Publicado: (2022)

Clausenidin induces caspase-dependent apoptosis in colon cancer
por: Waziri, Peter M., et al.
Publicado: (2016)

Kinetochore microtubules in PTK cells
Publicado: (1992)

Repeated phototherapeutic keratectomy (PTK) followed by PTK with photorefractive keratectomy for anterior granular corneal dystrophy
por: Sridhar, Uma, et al.
Publicado: (2020)

Interpolar spindle microtubules in PTK cells
Publicado: (1993)

Caspase-10 Is the Key Initiator Caspase Involved in Tributyltin-Mediated Apoptosis in Human Immune Cells
por: Krug, Harald F.
Publicado: (2012)

PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer
por: Wozniak, Darren J., et al.
Publicado: (2017)

PTK7 Faces the Wnt in Development and Disease
por: Berger, Hanna, et al.
Publicado: (2017)

Luffa echinata Roxb. Induced Apoptosis in Human Colon Cancer Cell (SW-480) in the Caspase-dependent Manner and Through a Mitochondrial Apoptosis Pathway
por: Shang, Li-Hua, et al.
Publicado: (2016)

DNA Aptamers as Molecular Probes for Colorectal Cancer Study
por: Sefah, Kwame, et al.
Publicado: (2010)

SRF Potentiates Colon Cancer Metastasis and Progression in a microRNA-214/PTK6-Dependent Manner
por: Li, Tao, et al.
Publicado: (2020)

E. adenophorum induces Cell Cycle Arrest and Apoptosis of Splenocytes through the Mitochondrial Pathway and Caspase Activation in Saanen Goats
por: He, Yajun, et al.
Publicado: (2015)

Study of the Molecular Recognition of Aptamers Selected through Ovarian Cancer Cell-SELEX
por: Van Simaeys, Dimitri, et al.
Publicado: (2010)

PTK2 and PTPN11 expression in myelodysplastic syndromes
por: Lazarini, Mariana, et al.
Publicado: (2013)

E. adenophorum Induces Cell Cycle and Apoptosis of Renal Cells through Mitochondrial Pathway and Caspase Activation in Saanen Goat
por: He, Yajun, et al.
Publicado: (2015)

Dicyanomethylene Substituted Benzothiazole Squaraines: The Efficiency of Photodynamic Therapy In Vitro and In Vivo
por: Wei, Yongbiao, et al.
Publicado: (2017)

Silencing of Pokemon Enhances Caspase-Dependent Apoptosis via Fas- and Mitochondria-Mediated Pathways in Hepatocellular Carcinoma Cells
por: Zhang, Yu-Qin, et al.
Publicado: (2013)

Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53
por: Weng, Chengyin, et al.
Publicado: (2019)

S-Nitrosylation of mitochondrial caspases
por: Mannick, Joan B., et al.
Publicado: (2001)

PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim
por: Park, Sun Hee, et al.
Publicado: (2015)

Swainsonine Induces Apoptosis through Mitochondrial Pathway and Caspase Activation in Goat Trophoblasts
por: Huang, Yong, et al.
Publicado: (2014)

Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment
por: Lopez-Cruzan, M, et al.
Publicado: (2016)

SRF Potentiates Colon Cancer Metastasis and Progression in a microRNA-214/PTK6-Dependent Manner [Retraction]
Publicado: (2022)

Selection of Aptamers Specific for Adipose Tissue
por: Liu, Jun, et al.
Publicado: (2012)

Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation
por: Lopergolo, A, et al.
Publicado: (2009)

Structural polarity of kinetochore microtubules in PtK1 cells
Publicado: (1981)

Ptk7 Marks the First Human Developmental EMT In Vitro
por: Chan, David N., et al.
Publicado: (2012)

Variants identified in PTK7 associated with neural tube defects
por: Lei, Yunping, et al.
Publicado: (2019)

PTK-7 Expression in Gastric Cancer: A Prognostic Determinant
por: Özçelik, Melike, et al.
Publicado: (2020)

Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis
por: Ricci, Jean-Ehrland, et al.
Publicado: (2003)

Econazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways
por: Sun, Juan, et al.
Publicado: (2014)

Porcine epidemic diarrhea virus induces caspase-independent apoptosis through activation of mitochondrial apoptosis-inducing factor
por: Kim, Youngnam, et al.
Publicado: (2014)

Caspase-4 is essential for saikosaponin a-induced apoptosis acting upstream of caspase-2 and γ-H2AX in colon cancer cells
por: Kang, Su Jin, et al.
Publicado: (2017)

Mycobacterium fortuitum-induced ER-Mitochondrial calcium dynamics promotes calpain/caspase-12/caspase-9 mediated apoptosis in fish macrophages
por: Datta, Debika, et al.
Publicado: (2018)

Oxidative Stress Induces Chondrocyte Apoptosis through Caspase-Dependent and Caspase-Independent Mitochondrial Pathways and the Antioxidant Mechanism of Angelica Sinensis Polysaccharide
por: Zhuang, Chao, et al.
Publicado: (2020)

Adaptors for disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease
por: Beck, Tim N., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_j8hgh8jnqv3lmtmgurejv5b2rb