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Silencing of PTK7 in Colon Cancer Cells: Caspase-10-Dependent Apoptosis via Mitochondrial Pathway

Protein tyrosine kinase-7 (PTK7) is a catalytically inactive receptor tyrosine kinase (RTK). PTK7 is upregulated in many common human cancers, including colon cancer, lung cancer, gastric cancer and acute myeloid leukemia. The reason for this up-regulation is not yet known. To explore the functional...

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Detalles Bibliográficos
Autores principales:	Meng, Ling, Sefah, Kwame, O'Donoghue, Meghan B., Zhu, Guizhi, Shangguan, Dihua, Noorali, Afshan, Chen, Yan, Zhou, Lei, Tan, Weihong
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982840/ https://www.ncbi.nlm.nih.gov/pubmed/21103379 http://dx.doi.org/10.1371/journal.pone.0014018

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