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Intraspecies Prion Transmission Results in Selection of Sheep Scrapie Strains

BACKGROUND: Sheep scrapie is caused by multiple prion strains, which have been classified on the basis of their biological characteristics in inbred mice. The heterogeneity of natural scrapie prions in individual sheep and in sheep flocks has not been clearly defined. METHODOLOGY/PRINCIPAL FINDINGS:...

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Detalles Bibliográficos
Autores principales:	Yokoyama, Takashi, Masujin, Kentaro, Schmerr, Mary Jo, Shu, Yujing, Okada, Hiroyuki, Iwamaru, Yoshifumi, Imamura, Morikazu, Matsuura, Yuichi, Murayama, Yuichi, Mohri, Shirou
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982847/ https://www.ncbi.nlm.nih.gov/pubmed/21103326 http://dx.doi.org/10.1371/journal.pone.0015450

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