Cargando…

Phosphorylation of a membrane curvature–sensing motif switches function of the HOPS subunit Vps41 in membrane tethering

Tethering factors are organelle-specific multisubunit protein complexes that identify, along with Rab guanosine triphosphatases, transport vesicles and trigger their SNARE-mediated fusion of specific transport vesicles with the target membranes. Little is known about how tethering factors discrimina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cabrera, Margarita, Langemeyer, Lars, Mari, Muriel, Rethmeier, Ralf, Orban, Ioan, Perz, Angela, Bröcker, Cornelia, Griffith, Janice, Klose, Daniel, Steinhoff, Heinz-Jürgen, Reggiori, Fulvio, Engelbrecht-Vandré, Siegfried, Ungermann, Christian
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983053/ https://www.ncbi.nlm.nih.gov/pubmed/21079247 http://dx.doi.org/10.1083/jcb.201004092

Ejemplares similares

Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery
por: Shvarev, Dmitry, et al.
Publicado: (2022)

How Vps41 HOPS between tethering functions
por: Short, Ben
Publicado: (2010)

Subunit Organisation of In Vitro Reconstituted HOPS and CORVET Multisubunit Membrane Tethering Complexes
por: Guo, Zhong, et al.
Publicado: (2013)

Multivalent Rab interactions determine tether-mediated membrane fusion
por: Lürick, Anna, et al.
Publicado: (2017)

Correction: Subunit Organisation of In Vitro Reconstituted HOPS and CORVET Multisubunit Membrane Tethering Complexes
por: Guo, Zhong, et al.
Publicado: (2014)

The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane
por: Ho, Ruoya, et al.
Publicado: (2015)

The N-Terminal Domains of Vps3 and Vps8 Are Critical for Localization and Function of the CORVET Tethering Complex on Endosomes
por: Epp, Nadine, et al.
Publicado: (2013)

Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking
por: Sanderson, Leslie E, et al.
Publicado: (2021)

Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt
por: Lőrincz, Péter, et al.
Publicado: (2019)

VPS18 recruits VPS41 to the human HOPS complex via a RING–RING interaction
por: Hunter, Morag R., et al.
Publicado: (2017)

Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure
por: Gao, Jieqiong, et al.
Publicado: (2018)

RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking
por: Lin, Xiaosi, et al.
Publicado: (2014)

The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex
por: LaGrassa, Tracy J., et al.
Publicado: (2005)

Corrigendum: RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking
por: Lin, Xiaosi, et al.
Publicado: (2015)

Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond
por: Borchers, Ann-Christin, et al.
Publicado: (2021)

AP‐3 vesicle uncoating occurs after HOPS‐dependent vacuole tethering
por: Schoppe, Jannis, et al.
Publicado: (2020)

C9orf72-catalyzed GTP loading of Rab39A enables HOPS-mediated membrane tethering and fusion in mammalian autophagy
por: Zhang, Shen, et al.
Publicado: (2023)

Parkinson’s disease–associated VPS35 mutant reduces mitochondrial membrane potential and impairs PINK1/Parkin-mediated mitophagy
por: Ma, Kai Yu, et al.
Publicado: (2021)

HOPS Initiates Vacuole Docking by Tethering Membranes before trans-SNARE Complex Assembly
por: Hickey, Christopher M., et al.
Publicado: (2010)

Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells
por: Zlatic, Stephanie A., et al.
Publicado: (2011)

Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport
por: Kvalvaag, Audun Sverre, et al.
Publicado: (2014)

Nuclear Pore Basket Proteins Are Tethered to the Nuclear Envelope and Can Regulate Membrane Curvature
por: Mészáros, Noémi, et al.
Publicado: (2015)

Membrane Origin for Autophagy
por: Reggiori, Fulvio
Publicado: (2006)

The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity
por: Gao, Jieqiong, et al.
Publicado: (2022)

Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation
por: van der Welle, Reini E N, et al.
Publicado: (2021)

The novel endosomal membrane protein Ema interacts with the class C Vps–HOPS complex to promote endosomal maturation
por: Kim, Sungsu, et al.
Publicado: (2010)

Membrane tethering
por: Chia, Pei Zhi Cheryl, et al.
Publicado: (2014)

A HOPS Protein, MoVps41, Is Crucially Important for Vacuolar Morphogenesis, Vegetative Growth, Reproduction and Virulence in Magnaporthe oryzae
por: Zhang, Xiaojie, et al.
Publicado: (2017)

Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes
por: Wartosch, Lena, et al.
Publicado: (2015)

Membrane Contact Sites in Autophagy
por: Zwilling, Emma, et al.
Publicado: (2022)

Fusion of tethered membranes can be driven by Sec18/NSF and Sec17/αSNAP without HOPS
por: Song, Hongki, et al.
Publicado: (2021)

The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation
por: Arlt, Henning, et al.
Publicado: (2023)

A novel in vitro assay reveals SNARE topology and the role of Ykt6 in autophagosome fusion with vacuoles
por: Gao, Jieqiong, et al.
Publicado: (2018)

Mechanisms of Membrane Curvature Generation in Membrane Traffic
por: Shin, Hye-Won, et al.
Publicado: (2012)

The puzzling origin of the autophagosomal membrane
por: Mari, Muriel, et al.
Publicado: (2011)

The HOPS complex subunit VPS39 controls ciliogenesis through autophagy
por: Iaconis, Daniela, et al.
Publicado: (2020)

The Organization and Function of the Phagophore-ER Membrane Contact Sites
por: Vargas Duarte, Prado, et al.
Publicado: (2023)

On Gaussian curvature and membrane fission
por: Rueda-Contreras, Mara Denisse, et al.
Publicado: (2021)

Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling
por: Segala, Gregory, et al.
Publicado: (2019)

Vacuolar protein sorting protein 41 (VPS41) at an intersection of endosomal traffic in neurodegenerative disease
por: Griffin, Edward F., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hfag6p88dpa1o39g1tl63jmovf