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Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment

We studied the function of plasma membrane microdomains defined by the proteins flotillin 1 and flotillin 2 in uropod formation and neutrophil chemotaxis. Flotillins become concentrated in the uropod of neutrophils after exposure to chemoattractants such as N-formyl-Met-Leu-Phe (fMLP). Here, we show...

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Detalles Bibliográficos
Autores principales: Ludwig, Alexander, Otto, Grant P., Riento, Kirsi, Hams, Emily, Fallon, Padraic G., Nichols, Ben J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983060/
https://www.ncbi.nlm.nih.gov/pubmed/21059848
http://dx.doi.org/10.1083/jcb.201005140