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Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment
We studied the function of plasma membrane microdomains defined by the proteins flotillin 1 and flotillin 2 in uropod formation and neutrophil chemotaxis. Flotillins become concentrated in the uropod of neutrophils after exposure to chemoattractants such as N-formyl-Met-Leu-Phe (fMLP). Here, we show...
Autores principales: | Ludwig, Alexander, Otto, Grant P., Riento, Kirsi, Hams, Emily, Fallon, Padraic G., Nichols, Ben J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983060/ https://www.ncbi.nlm.nih.gov/pubmed/21059848 http://dx.doi.org/10.1083/jcb.201005140 |
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