N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide

The title compound, C(15)H(14)ClNO(2), was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hy­droxy­phen­yl)acetamide. It crystallizes as non-planar discrete mol­ecules [the peripheral 3-chloro-4-hy­droxy­phenyl and benzyl groups...

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Detalles Bibliográficos
Autores principales: Davis, Rohan A., Healy, Peter C.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983291/
https://www.ncbi.nlm.nih.gov/pubmed/21587515
http://dx.doi.org/10.1107/S1600536810035397
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author Davis, Rohan A.
Healy, Peter C.
author_facet Davis, Rohan A.
Healy, Peter C.
author_sort Davis, Rohan A.
collection PubMed
description The title compound, C(15)H(14)ClNO(2), was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hy­droxy­phen­yl)acetamide. It crystallizes as non-planar discrete mol­ecules [the peripheral 3-chloro-4-hy­droxy­phenyl and benzyl groups are twisted out of the plane of the central acetamide group, with N—C—C—C and C—C—C—C torsion angles of −58.8 (3) and 65.0 (2)°, respectively] linked by inter­molecular N—H⋯O and O—H⋯O hydrogen bonds.
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spelling pubmed-29832912010-12-30 N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide Davis, Rohan A. Healy, Peter C. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(15)H(14)ClNO(2), was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hy­droxy­phen­yl)acetamide. It crystallizes as non-planar discrete mol­ecules [the peripheral 3-chloro-4-hy­droxy­phenyl and benzyl groups are twisted out of the plane of the central acetamide group, with N—C—C—C and C—C—C—C torsion angles of −58.8 (3) and 65.0 (2)°, respectively] linked by inter­molecular N—H⋯O and O—H⋯O hydrogen bonds. International Union of Crystallography 2010-09-08 /pmc/articles/PMC2983291/ /pubmed/21587515 http://dx.doi.org/10.1107/S1600536810035397 Text en © Davis and Healy 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Davis, Rohan A.
Healy, Peter C.
N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide
title N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide
title_full N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide
title_fullStr N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide
title_full_unstemmed N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide
title_short N-Benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide
title_sort n-benzyl-2-(3-chloro-4-hy­droxy­phen­yl)acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983291/
https://www.ncbi.nlm.nih.gov/pubmed/21587515
http://dx.doi.org/10.1107/S1600536810035397
work_keys_str_mv AT davisrohana nbenzyl23chloro4hydroxyphenylacetamide
AT healypeterc nbenzyl23chloro4hydroxyphenylacetamide

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