Cargando…

5,6-Dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione

In the title compound, C(33)H(28)N(2)O(4), the central pyrrolidine ring adopts a half-chair conformation. Both the indolinone and indanone groups are twisted, with their five-membered rings adopting a half-chair and an envelope conformation, respectively. The two benzene rings and the mean plane of...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali, Mohamed Ashraf, Ismail, Rusli, Tan, Soo Choon, Yeap, Chin Sing, Fun, Hoong-Kun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983396/
https://www.ncbi.nlm.nih.gov/pubmed/21587525
http://dx.doi.org/10.1107/S1600536810035865
_version_ 1782191872522846208
author Ali, Mohamed Ashraf
Ismail, Rusli
Tan, Soo Choon
Yeap, Chin Sing
Fun, Hoong-Kun
author_facet Ali, Mohamed Ashraf
Ismail, Rusli
Tan, Soo Choon
Yeap, Chin Sing
Fun, Hoong-Kun
author_sort Ali, Mohamed Ashraf
collection PubMed
description In the title compound, C(33)H(28)N(2)O(4), the central pyrrolidine ring adopts a half-chair conformation. Both the indolinone and indanone groups are twisted, with their five-membered rings adopting a half-chair and an envelope conformation, respectively. The two benzene rings and the mean plane of the indolinone and indanone groups make dihedral angles of 71.98 (10), 84.32 (10), 86.26 (9) and 78.50 (9)°, respectively, with the central pyrrolidine ring. Intra­molecular C—H⋯O hydrogen bonds stabilize the mol­ecular conformation. In the crystal, pairs of inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into centrosymmetric dimers. The dimers are inter­connected into ribbons propagating along [110] via weak inter­molecular C—H⋯O hydrogen bonds. Weak inter­molecular C—H⋯π and π–π [centroid–centroid distance = 3.6509 (11) Å] inter­actions are also observed.
format Text
id pubmed-2983396
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29833962010-12-30 5,6-Dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione Ali, Mohamed Ashraf Ismail, Rusli Tan, Soo Choon Yeap, Chin Sing Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(33)H(28)N(2)O(4), the central pyrrolidine ring adopts a half-chair conformation. Both the indolinone and indanone groups are twisted, with their five-membered rings adopting a half-chair and an envelope conformation, respectively. The two benzene rings and the mean plane of the indolinone and indanone groups make dihedral angles of 71.98 (10), 84.32 (10), 86.26 (9) and 78.50 (9)°, respectively, with the central pyrrolidine ring. Intra­molecular C—H⋯O hydrogen bonds stabilize the mol­ecular conformation. In the crystal, pairs of inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into centrosymmetric dimers. The dimers are inter­connected into ribbons propagating along [110] via weak inter­molecular C—H⋯O hydrogen bonds. Weak inter­molecular C—H⋯π and π–π [centroid–centroid distance = 3.6509 (11) Å] inter­actions are also observed. International Union of Crystallography 2010-09-11 /pmc/articles/PMC2983396/ /pubmed/21587525 http://dx.doi.org/10.1107/S1600536810035865 Text en © Ali et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ali, Mohamed Ashraf
Ismail, Rusli
Tan, Soo Choon
Yeap, Chin Sing
Fun, Hoong-Kun
5,6-Dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
title 5,6-Dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
title_full 5,6-Dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
title_fullStr 5,6-Dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
title_full_unstemmed 5,6-Dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
title_short 5,6-Dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
title_sort 5,6-dimeth­oxy-4′,5′-diphenyl­indane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983396/
https://www.ncbi.nlm.nih.gov/pubmed/21587525
http://dx.doi.org/10.1107/S1600536810035865
work_keys_str_mv AT alimohamedashraf 56dimethoxy45diphenylindane2spiro3pyrrolidine2spiro3indoline12dione
AT ismailrusli 56dimethoxy45diphenylindane2spiro3pyrrolidine2spiro3indoline12dione
AT tansoochoon 56dimethoxy45diphenylindane2spiro3pyrrolidine2spiro3indoline12dione
AT yeapchinsing 56dimethoxy45diphenylindane2spiro3pyrrolidine2spiro3indoline12dione
AT funhoongkun 56dimethoxy45diphenylindane2spiro3pyrrolidine2spiro3indoline12dione