Dimethyl 3,3′-diphenyl-2,2′-[(S)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate

The title compound, C(26)H(26)N(2)O(6)S·C(4)H(8)O, a solvated bis-amide derivative, is also a chiral amino acid ester with l-phenyl­alanine methyl ester groups as amine substituents. The thio­phene-2,5-dicarboxamide core approximates C (2) point symmetry. The tetra­hydro­furan solvent mol­ecule is l...

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Detalles Bibliográficos
Autores principales: Xia, GuangMing, Liu, Jing, Li, Zhen, Ji, MuWei, Sun, GuoXin
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983431/
https://www.ncbi.nlm.nih.gov/pubmed/21587488
http://dx.doi.org/10.1107/S1600536810034410
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author Xia, GuangMing
Liu, Jing
Li, Zhen
Ji, MuWei
Sun, GuoXin
author_facet Xia, GuangMing
Liu, Jing
Li, Zhen
Ji, MuWei
Sun, GuoXin
author_sort Xia, GuangMing
collection PubMed
description The title compound, C(26)H(26)N(2)O(6)S·C(4)H(8)O, a solvated bis-amide derivative, is also a chiral amino acid ester with l-phenyl­alanine methyl ester groups as amine substituents. The thio­phene-2,5-dicarboxamide core approximates C (2) point symmetry. The tetra­hydro­furan solvent mol­ecule is linked to the main mol­ecule through an inter­molecular N—H⋯O hydrogen bond. The central ring makes dihedral angles of 90.0 (2) and 76.5 (2)° with the pendant rings.
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spelling pubmed-29834312010-12-30 Dimethyl 3,3′-diphenyl-2,2′-[(S)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate Xia, GuangMing Liu, Jing Li, Zhen Ji, MuWei Sun, GuoXin Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(26)H(26)N(2)O(6)S·C(4)H(8)O, a solvated bis-amide derivative, is also a chiral amino acid ester with l-phenyl­alanine methyl ester groups as amine substituents. The thio­phene-2,5-dicarboxamide core approximates C (2) point symmetry. The tetra­hydro­furan solvent mol­ecule is linked to the main mol­ecule through an inter­molecular N—H⋯O hydrogen bond. The central ring makes dihedral angles of 90.0 (2) and 76.5 (2)° with the pendant rings. International Union of Crystallography 2010-09-04 /pmc/articles/PMC2983431/ /pubmed/21587488 http://dx.doi.org/10.1107/S1600536810034410 Text en © Xia et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Xia, GuangMing
Liu, Jing
Li, Zhen
Ji, MuWei
Sun, GuoXin
Dimethyl 3,3′-diphenyl-2,2′-[(S)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate
title Dimethyl 3,3′-diphenyl-2,2′-[(S)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate
title_full Dimethyl 3,3′-diphenyl-2,2′-[(S)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate
title_fullStr Dimethyl 3,3′-diphenyl-2,2′-[(S)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate
title_full_unstemmed Dimethyl 3,3′-diphenyl-2,2′-[(S)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate
title_short Dimethyl 3,3′-diphenyl-2,2′-[(S)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate
title_sort dimethyl 3,3′-diphenyl-2,2′-[(s)-thio­phene-2,5-diylbis(carbonyl­aza­nedi­yl)]dipropano­ate tetra­hydro­furan monosolvate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983431/
https://www.ncbi.nlm.nih.gov/pubmed/21587488
http://dx.doi.org/10.1107/S1600536810034410
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