3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine

The title compound, C(15)H(14)ClF(3)N(4), was synthesized from 3,6-dichloro­pyridazine and 1-[3-(trifluoro­meth­yl)phen­yl]piper­azine. The piperazine ring is flanked by 3-chloro­pyridazine and 3-trifluoro­methyl­phenyl rings and adopts a chair conformation, whereas the 3-chloro­pyridazine and 3-tri...

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Detalles Bibliográficos
Autores principales: Arslan, Hakan, Utku, Semra, Hardcastle, Kenneth I., Gökçe, Mehtap, Lense, Sheri
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983628/
https://www.ncbi.nlm.nih.gov/pubmed/21580304
http://dx.doi.org/10.1107/S1600536810004137
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author Arslan, Hakan
Utku, Semra
Hardcastle, Kenneth I.
Gökçe, Mehtap
Lense, Sheri
author_facet Arslan, Hakan
Utku, Semra
Hardcastle, Kenneth I.
Gökçe, Mehtap
Lense, Sheri
author_sort Arslan, Hakan
collection PubMed
description The title compound, C(15)H(14)ClF(3)N(4), was synthesized from 3,6-dichloro­pyridazine and 1-[3-(trifluoro­meth­yl)phen­yl]piper­azine. The piperazine ring is flanked by 3-chloro­pyridazine and 3-trifluoro­methyl­phenyl rings and adopts a chair conformation, whereas the 3-chloro­pyridazine and 3-trifluoro­methyl­phenyl rings are planar, with maximum deviations of 0.0069 (13) and 0.0133 (14) Å, respectively. The crystal structure is stabilized by weak inter­molecular C—H⋯N hydrogen-bond inter­actions.
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spelling pubmed-29836282010-12-30 3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine Arslan, Hakan Utku, Semra Hardcastle, Kenneth I. Gökçe, Mehtap Lense, Sheri Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(15)H(14)ClF(3)N(4), was synthesized from 3,6-dichloro­pyridazine and 1-[3-(trifluoro­meth­yl)phen­yl]piper­azine. The piperazine ring is flanked by 3-chloro­pyridazine and 3-trifluoro­methyl­phenyl rings and adopts a chair conformation, whereas the 3-chloro­pyridazine and 3-trifluoro­methyl­phenyl rings are planar, with maximum deviations of 0.0069 (13) and 0.0133 (14) Å, respectively. The crystal structure is stabilized by weak inter­molecular C—H⋯N hydrogen-bond inter­actions. International Union of Crystallography 2010-02-06 /pmc/articles/PMC2983628/ /pubmed/21580304 http://dx.doi.org/10.1107/S1600536810004137 Text en © Arslan et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Arslan, Hakan
Utku, Semra
Hardcastle, Kenneth I.
Gökçe, Mehtap
Lense, Sheri
3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine
title 3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine
title_full 3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine
title_fullStr 3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine
title_full_unstemmed 3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine
title_short 3-Chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine
title_sort 3-chloro-6-{4-[3-(trifluoro­meth­yl)phen­yl]piperazin-1-yl}pyridazine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983628/
https://www.ncbi.nlm.nih.gov/pubmed/21580304
http://dx.doi.org/10.1107/S1600536810004137
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AT hardcastlekennethi 3chloro643trifluoromethylphenylpiperazin1ylpyridazine
AT gokcemehtap 3chloro643trifluoromethylphenylpiperazin1ylpyridazine
AT lensesheri 3chloro643trifluoromethylphenylpiperazin1ylpyridazine

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