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4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline
An L-shaped conformation is found in the title molecule, C(20)H(20)F(6)N(2)O, the C—C—C—C torsion angle linking the two fused-ring systems being −92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the pipe...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983630/ https://www.ncbi.nlm.nih.gov/pubmed/21580439 http://dx.doi.org/10.1107/S1600536810006562 |
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author | Wardell, James L. Wardell, Solange M. S. V. Tiekink, Edward R. T. |
author_facet | Wardell, James L. Wardell, Solange M. S. V. Tiekink, Edward R. T. |
author_sort | Wardell, James L. |
collection | PubMed |
description | An L-shaped conformation is found in the title molecule, C(20)H(20)F(6)N(2)O, the C—C—C—C torsion angle linking the two fused-ring systems being −92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the piperidine ring has a chair conformation. Supramolecular chains are found in the crystal structure that are sustained by C—H⋯π and π–π [3.6089 (10) Å] interactions. |
format | Text |
id | pubmed-2983630 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29836302010-12-30 4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline Wardell, James L. Wardell, Solange M. S. V. Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers An L-shaped conformation is found in the title molecule, C(20)H(20)F(6)N(2)O, the C—C—C—C torsion angle linking the two fused-ring systems being −92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the piperidine ring has a chair conformation. Supramolecular chains are found in the crystal structure that are sustained by C—H⋯π and π–π [3.6089 (10) Å] interactions. International Union of Crystallography 2010-02-27 /pmc/articles/PMC2983630/ /pubmed/21580439 http://dx.doi.org/10.1107/S1600536810006562 Text en © Wardell et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Wardell, James L. Wardell, Solange M. S. V. Tiekink, Edward R. T. 4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline |
title | 4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline |
title_full | 4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline |
title_fullStr | 4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline |
title_full_unstemmed | 4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline |
title_short | 4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline |
title_sort | 4-(3,3-dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983630/ https://www.ncbi.nlm.nih.gov/pubmed/21580439 http://dx.doi.org/10.1107/S1600536810006562 |
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