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4-(3,3-Dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline

An L-shaped conformation is found in the title mol­ecule, C(20)H(20)F(6)N(2)O, the C—C—C—C torsion angle linking the two fused-ring systems being −92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the pipe...

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Detalles Bibliográficos
Autores principales: Wardell, James L., Wardell, Solange M. S. V., Tiekink, Edward R. T.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983630/
https://www.ncbi.nlm.nih.gov/pubmed/21580439
http://dx.doi.org/10.1107/S1600536810006562
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author Wardell, James L.
Wardell, Solange M. S. V.
Tiekink, Edward R. T.
author_facet Wardell, James L.
Wardell, Solange M. S. V.
Tiekink, Edward R. T.
author_sort Wardell, James L.
collection PubMed
description An L-shaped conformation is found in the title mol­ecule, C(20)H(20)F(6)N(2)O, the C—C—C—C torsion angle linking the two fused-ring systems being −92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the piperidine ring has a chair conformation. Supra­molecular chains are found in the crystal structure that are sustained by C—H⋯π and π–π [3.6089 (10) Å] inter­actions.
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spelling pubmed-29836302010-12-30 4-(3,3-Dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline Wardell, James L. Wardell, Solange M. S. V. Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers An L-shaped conformation is found in the title mol­ecule, C(20)H(20)F(6)N(2)O, the C—C—C—C torsion angle linking the two fused-ring systems being −92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the piperidine ring has a chair conformation. Supra­molecular chains are found in the crystal structure that are sustained by C—H⋯π and π–π [3.6089 (10) Å] inter­actions. International Union of Crystallography 2010-02-27 /pmc/articles/PMC2983630/ /pubmed/21580439 http://dx.doi.org/10.1107/S1600536810006562 Text en © Wardell et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wardell, James L.
Wardell, Solange M. S. V.
Tiekink, Edward R. T.
4-(3,3-Dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline
title 4-(3,3-Dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline
title_full 4-(3,3-Dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline
title_fullStr 4-(3,3-Dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline
title_full_unstemmed 4-(3,3-Dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline
title_short 4-(3,3-Dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline
title_sort 4-(3,3-dimethyl­perhydro-1,3-oxa­zolo[3,4-a]pyridin-1-yl)-2,8-bis­(tri­fluoro­meth­yl)quinoline
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983630/
https://www.ncbi.nlm.nih.gov/pubmed/21580439
http://dx.doi.org/10.1107/S1600536810006562
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AT tiekinkedwardrt 433dimethylperhydro13oxazolo34apyridin1yl28bistrifluoromethylquinoline