3β-Chloro­cholest-5-en-7-one

The title compound, C(27)H(43)ClO, is a steroid derivative composed of a saturated carbon fused-ring framework with an alkyl side chain. The A and C rings have chair conformations and the B and D rings assume half-chair conformations. The cholesterol side chain is fully extended with a gauche, trans...

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Autores principales: Khan, Mohd. Shaheen, Sulaiman, Othman, Hashim, Rokiah, Hemamalini, Madhukar, Fun, Hoong-Kun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983643/
https://www.ncbi.nlm.nih.gov/pubmed/21580431
http://dx.doi.org/10.1107/S1600536810006380
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author Khan, Mohd. Shaheen
Sulaiman, Othman
Hashim, Rokiah
Hemamalini, Madhukar
Fun, Hoong-Kun
author_facet Khan, Mohd. Shaheen
Sulaiman, Othman
Hashim, Rokiah
Hemamalini, Madhukar
Fun, Hoong-Kun
author_sort Khan, Mohd. Shaheen
collection PubMed
description The title compound, C(27)H(43)ClO, is a steroid derivative composed of a saturated carbon fused-ring framework with an alkyl side chain. The A and C rings have chair conformations and the B and D rings assume half-chair conformations. The cholesterol side chain is fully extended with a gauche, trans conformation of the terminal methyl groups. In the crystal structure, the molecules are aligned in an antiparallel fashion, forming alternate layers. These layers are then linked via C—H⋯O hydrogen bonds, forming a three-dimensional network.
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spelling pubmed-29836432010-12-30 3β-Chloro­cholest-5-en-7-one Khan, Mohd. Shaheen Sulaiman, Othman Hashim, Rokiah Hemamalini, Madhukar Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(27)H(43)ClO, is a steroid derivative composed of a saturated carbon fused-ring framework with an alkyl side chain. The A and C rings have chair conformations and the B and D rings assume half-chair conformations. The cholesterol side chain is fully extended with a gauche, trans conformation of the terminal methyl groups. In the crystal structure, the molecules are aligned in an antiparallel fashion, forming alternate layers. These layers are then linked via C—H⋯O hydrogen bonds, forming a three-dimensional network. International Union of Crystallography 2010-02-27 /pmc/articles/PMC2983643/ /pubmed/21580431 http://dx.doi.org/10.1107/S1600536810006380 Text en © Khan et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Khan, Mohd. Shaheen
Sulaiman, Othman
Hashim, Rokiah
Hemamalini, Madhukar
Fun, Hoong-Kun
3β-Chloro­cholest-5-en-7-one
title 3β-Chloro­cholest-5-en-7-one
title_full 3β-Chloro­cholest-5-en-7-one
title_fullStr 3β-Chloro­cholest-5-en-7-one
title_full_unstemmed 3β-Chloro­cholest-5-en-7-one
title_short 3β-Chloro­cholest-5-en-7-one
title_sort 3β-chloro­cholest-5-en-7-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983643/
https://www.ncbi.nlm.nih.gov/pubmed/21580431
http://dx.doi.org/10.1107/S1600536810006380
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AT sulaimanothman 3bchlorocholest5en7one
AT hashimrokiah 3bchlorocholest5en7one
AT hemamalinimadhukar 3bchlorocholest5en7one
AT funhoongkun 3bchlorocholest5en7one

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