4-(4-Chloro­phen­yl)piperidin-4-ol

In the title compound, C(11)H(14)ClNO, the piperidine ring adopts a chair conformation: the hydroxyl substituent and the N-bound H atom occupy the axial positions, while the benzene ring occupies the equatorial position. In the crystal, the mol­ecules are linked into a centrosymmetric tetra­mer thro...

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Detalles Bibliográficos
Autores principales: Dutkiewicz, Grzegorz, Siddaraju, B. P., Yathirajan, H. S., Siddegowda, M. S., Kubicki, Maciej
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983646/
https://www.ncbi.nlm.nih.gov/pubmed/21580330
http://dx.doi.org/10.1107/S1600536810004216
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author Dutkiewicz, Grzegorz
Siddaraju, B. P.
Yathirajan, H. S.
Siddegowda, M. S.
Kubicki, Maciej
author_facet Dutkiewicz, Grzegorz
Siddaraju, B. P.
Yathirajan, H. S.
Siddegowda, M. S.
Kubicki, Maciej
author_sort Dutkiewicz, Grzegorz
collection PubMed
description In the title compound, C(11)H(14)ClNO, the piperidine ring adopts a chair conformation: the hydroxyl substituent and the N-bound H atom occupy the axial positions, while the benzene ring occupies the equatorial position. In the crystal, the mol­ecules are linked into a centrosymmetric tetra­mer through strong O—H⋯N and weak N—H⋯O hydrogen bonds; the N and O atoms act as both donor and acceptor for these inter­actions. The tetra­mers are further joined by hydrogen bonds into a layer parallel to (100).
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spelling pubmed-29836462010-12-30 4-(4-Chloro­phen­yl)piperidin-4-ol Dutkiewicz, Grzegorz Siddaraju, B. P. Yathirajan, H. S. Siddegowda, M. S. Kubicki, Maciej Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(11)H(14)ClNO, the piperidine ring adopts a chair conformation: the hydroxyl substituent and the N-bound H atom occupy the axial positions, while the benzene ring occupies the equatorial position. In the crystal, the mol­ecules are linked into a centrosymmetric tetra­mer through strong O—H⋯N and weak N—H⋯O hydrogen bonds; the N and O atoms act as both donor and acceptor for these inter­actions. The tetra­mers are further joined by hydrogen bonds into a layer parallel to (100). International Union of Crystallography 2010-02-06 /pmc/articles/PMC2983646/ /pubmed/21580330 http://dx.doi.org/10.1107/S1600536810004216 Text en © Dutkiewicz et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Dutkiewicz, Grzegorz
Siddaraju, B. P.
Yathirajan, H. S.
Siddegowda, M. S.
Kubicki, Maciej
4-(4-Chloro­phen­yl)piperidin-4-ol
title 4-(4-Chloro­phen­yl)piperidin-4-ol
title_full 4-(4-Chloro­phen­yl)piperidin-4-ol
title_fullStr 4-(4-Chloro­phen­yl)piperidin-4-ol
title_full_unstemmed 4-(4-Chloro­phen­yl)piperidin-4-ol
title_short 4-(4-Chloro­phen­yl)piperidin-4-ol
title_sort 4-(4-chloro­phen­yl)piperidin-4-ol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983646/
https://www.ncbi.nlm.nih.gov/pubmed/21580330
http://dx.doi.org/10.1107/S1600536810004216
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AT yathirajanhs 44chlorophenylpiperidin4ol
AT siddegowdams 44chlorophenylpiperidin4ol
AT kubickimaciej 44chlorophenylpiperidin4ol

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