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(3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine)
In the racemic title compound, C(22)H(23)NO(7), the dihedral angle between the fused ring systems is 51.87 (6)°. Two of the methoxy groups are disordered over two orientations in 0.688 (5):0.312 (5) and 0.672 (15):0.328 (15) ratios. In the crystal, weak C—H⋯O interactions link the molecules....
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983739/ https://www.ncbi.nlm.nih.gov/pubmed/21580338 http://dx.doi.org/10.1107/S1600536810003958 |
| _version_ | 1782191945858154496 |
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| author | von Langermann, Jan Lorenz, Heike Boehm, Oliver Flemming, Anke Bernsdorf, Arne Köckerling, Martin Schinzer, Dieter Seidel-Morgenstern, Andreas |
| author_facet | von Langermann, Jan Lorenz, Heike Boehm, Oliver Flemming, Anke Bernsdorf, Arne Köckerling, Martin Schinzer, Dieter Seidel-Morgenstern, Andreas |
| author_sort | von Langermann, Jan |
| collection | PubMed |
| description | In the racemic title compound, C(22)H(23)NO(7), the dihedral angle between the fused ring systems is 51.87 (6)°. Two of the methoxy groups are disordered over two orientations in 0.688 (5):0.312 (5) and 0.672 (15):0.328 (15) ratios. In the crystal, weak C—H⋯O interactions link the molecules. |
| format | Text |
| id | pubmed-2983739 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2010 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-29837392010-12-30 (3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine) von Langermann, Jan Lorenz, Heike Boehm, Oliver Flemming, Anke Bernsdorf, Arne Köckerling, Martin Schinzer, Dieter Seidel-Morgenstern, Andreas Acta Crystallogr Sect E Struct Rep Online Organic Papers In the racemic title compound, C(22)H(23)NO(7), the dihedral angle between the fused ring systems is 51.87 (6)°. Two of the methoxy groups are disordered over two orientations in 0.688 (5):0.312 (5) and 0.672 (15):0.328 (15) ratios. In the crystal, weak C—H⋯O interactions link the molecules. International Union of Crystallography 2010-02-10 /pmc/articles/PMC2983739/ /pubmed/21580338 http://dx.doi.org/10.1107/S1600536810003958 Text en © Langermann et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers von Langermann, Jan Lorenz, Heike Boehm, Oliver Flemming, Anke Bernsdorf, Arne Köckerling, Martin Schinzer, Dieter Seidel-Morgenstern, Andreas (3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine) |
| title | (3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine) |
| title_full | (3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine) |
| title_fullStr | (3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine) |
| title_full_unstemmed | (3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine) |
| title_short | (3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine) |
| title_sort | (3r*,5′s*)-6,7-dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3h)-one (racemic α-noscapine) |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983739/ https://www.ncbi.nlm.nih.gov/pubmed/21580338 http://dx.doi.org/10.1107/S1600536810003958 |
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