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4-Hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1H)-one
In the title compound, C(28)H(23)N(3)O(4), the dihedral angle between the quinoline and indole ring systems is 29.30 (5)°. The pyrrolidine ring adopts a twist conformation. An intramolecular O—H⋯O hydrogen bond generates an S(6) ring motif. A weak intramolecular C3—H3⋯O3 interaction is also obser...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983794/ https://www.ncbi.nlm.nih.gov/pubmed/21580756 http://dx.doi.org/10.1107/S1600536810010500 |
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author | Revathi, K. Sankaran, M. Ramesh, P. Mohan, P. S. Ponnuswamy, M. N. |
author_facet | Revathi, K. Sankaran, M. Ramesh, P. Mohan, P. S. Ponnuswamy, M. N. |
author_sort | Revathi, K. |
collection | PubMed |
description | In the title compound, C(28)H(23)N(3)O(4), the dihedral angle between the quinoline and indole ring systems is 29.30 (5)°. The pyrrolidine ring adopts a twist conformation. An intramolecular O—H⋯O hydrogen bond generates an S(6) ring motif. A weak intramolecular C3—H3⋯O3 interaction is also observed. In the crystal, molecules are linked by two sets of N—H⋯O hydrogen bonds, forming centrosymmetric dimers containing two R (2) (2)(8) ring motifs. The dimers are linked via C—H⋯π interactions. |
format | Text |
id | pubmed-2983794 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29837942010-12-30 4-Hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1H)-one Revathi, K. Sankaran, M. Ramesh, P. Mohan, P. S. Ponnuswamy, M. N. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(28)H(23)N(3)O(4), the dihedral angle between the quinoline and indole ring systems is 29.30 (5)°. The pyrrolidine ring adopts a twist conformation. An intramolecular O—H⋯O hydrogen bond generates an S(6) ring motif. A weak intramolecular C3—H3⋯O3 interaction is also observed. In the crystal, molecules are linked by two sets of N—H⋯O hydrogen bonds, forming centrosymmetric dimers containing two R (2) (2)(8) ring motifs. The dimers are linked via C—H⋯π interactions. International Union of Crystallography 2010-03-27 /pmc/articles/PMC2983794/ /pubmed/21580756 http://dx.doi.org/10.1107/S1600536810010500 Text en © Revathi et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Revathi, K. Sankaran, M. Ramesh, P. Mohan, P. S. Ponnuswamy, M. N. 4-Hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1H)-one |
title | 4-Hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1H)-one |
title_full | 4-Hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1H)-one |
title_fullStr | 4-Hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1H)-one |
title_full_unstemmed | 4-Hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1H)-one |
title_short | 4-Hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1H)-one |
title_sort | 4-hydroxy-3-(1′-methyl-2-oxo-4′-phenylspiro[indoline-3,2′-pyrrolidine]-3′-ylcarbonyl)quinolin-2(1h)-one |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983794/ https://www.ncbi.nlm.nih.gov/pubmed/21580756 http://dx.doi.org/10.1107/S1600536810010500 |
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