Cargando…
4-[(2,4-Dimethyl-1,3-oxazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione
In the title isoquinolinedione derivative, C(16)H(16)N(2)O(4), the piperidine ring in the tetrahydroisoquinoline unit adopts a half-boat conformation. The essentially planar oxazole ring [maximum deviation = 0.004 (2) Å] is inclined at a dihedral angle of 36.00 (8)° to the tetrahydroisoquinoline...
Autores principales: | , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983926/ https://www.ncbi.nlm.nih.gov/pubmed/21580572 http://dx.doi.org/10.1107/S1600536810007397 |
Sumario: | In the title isoquinolinedione derivative, C(16)H(16)N(2)O(4), the piperidine ring in the tetrahydroisoquinoline unit adopts a half-boat conformation. The essentially planar oxazole ring [maximum deviation = 0.004 (2) Å] is inclined at a dihedral angle of 36.00 (8)° to the tetrahydroisoquinoline unit. In the crystal structure, pairs of intermolecular C—H⋯O and O—H⋯N interactions link the molecules into chains incorporating R (2) (2)(9) ring motifs. Two neighbouring chains are further interconnected by intermolecular C—H⋯O interactions into chains two molecules wide along the a axis. |
---|