2-Hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate

The title compound, C(15)H(14)N(2)O(3)·H(2)O, consists of a benzodiazepinedione system fused to a pyrrole system. The seven-membered ring adopts a boat-shaped conformation (with the methine C atom as the prow); the five-membered ring adopts an enveloped-shaped conformation (with the hydr­oxy-bearing...

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Autores principales: Ourahou, S., Chammache, M., Zouihri, H., Essassi, El Mokhtar, Ng, Seik Weng
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983934/
https://www.ncbi.nlm.nih.gov/pubmed/21580577
http://dx.doi.org/10.1107/S1600536810006896
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author Ourahou, S.
Chammache, M.
Zouihri, H.
Essassi, El Mokhtar
Ng, Seik Weng
author_facet Ourahou, S.
Chammache, M.
Zouihri, H.
Essassi, El Mokhtar
Ng, Seik Weng
author_sort Ourahou, S.
collection PubMed
description The title compound, C(15)H(14)N(2)O(3)·H(2)O, consists of a benzodiazepinedione system fused to a pyrrole system. The seven-membered ring adopts a boat-shaped conformation (with the methine C atom as the prow); the five-membered ring adopts an enveloped-shaped conformation (with the hydr­oxy-bearing C atom as the flap). In the crystal, adjacent mol­ecules are linked by O—H⋯O hydrogen bonds into sheets parallel to (102). In addition, C(acetyl­inic)—H⋯O hydrogen bonds occur.
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spelling pubmed-29839342010-12-30 2-Hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate Ourahou, S. Chammache, M. Zouihri, H. Essassi, El Mokhtar Ng, Seik Weng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(15)H(14)N(2)O(3)·H(2)O, consists of a benzodiazepinedione system fused to a pyrrole system. The seven-membered ring adopts a boat-shaped conformation (with the methine C atom as the prow); the five-membered ring adopts an enveloped-shaped conformation (with the hydr­oxy-bearing C atom as the flap). In the crystal, adjacent mol­ecules are linked by O—H⋯O hydrogen bonds into sheets parallel to (102). In addition, C(acetyl­inic)—H⋯O hydrogen bonds occur. International Union of Crystallography 2010-03-03 /pmc/articles/PMC2983934/ /pubmed/21580577 http://dx.doi.org/10.1107/S1600536810006896 Text en © Ourahou et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ourahou, S.
Chammache, M.
Zouihri, H.
Essassi, El Mokhtar
Ng, Seik Weng
2-Hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate
title 2-Hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate
title_full 2-Hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate
title_fullStr 2-Hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate
title_full_unstemmed 2-Hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate
title_short 2-Hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate
title_sort 2-hydr­oxy-10-propargylpyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione monohydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983934/
https://www.ncbi.nlm.nih.gov/pubmed/21580577
http://dx.doi.org/10.1107/S1600536810006896
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