15α,20β-Dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene

The title compound, C(21)H(30)O(6), a natural ent-kaurane diterpenoid, was obtained from the medicinal plant Isodon serra. The five rings in the mol­ecule exhibit the expected cis and trans junctions. The three six-membered rings adopt chair, twist-boat and boat conformations, while two five-membere...

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Detalles Bibliográficos
Autores principales: Yan, Fu-Lin, Zhan, He-Qin, Feng, Chuang, Di, Xue-Mei
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984011/
https://www.ncbi.nlm.nih.gov/pubmed/21580740
http://dx.doi.org/10.1107/S1600536810010573
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author Yan, Fu-Lin
Zhan, He-Qin
Feng, Chuang
Di, Xue-Mei
author_facet Yan, Fu-Lin
Zhan, He-Qin
Feng, Chuang
Di, Xue-Mei
author_sort Yan, Fu-Lin
collection PubMed
description The title compound, C(21)H(30)O(6), a natural ent-kaurane diterpenoid, was obtained from the medicinal plant Isodon serra. The five rings in the mol­ecule exhibit the expected cis and trans junctions. The three six-membered rings adopt chair, twist-boat and boat conformations, while two five-membered rings adopt envelope conformations. There are two mol­ecules in the asymmetric unit, related by a non-crystallographic twofold screw axis; the main difference is in the different degrees of distortion of ring B. In the crystal, the mol­ecules are linked by inter­molecular O—H⋯O hydrogen bonds, forming chains along the b axis.
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spelling pubmed-29840112010-12-30 15α,20β-Dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene Yan, Fu-Lin Zhan, He-Qin Feng, Chuang Di, Xue-Mei Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(21)H(30)O(6), a natural ent-kaurane diterpenoid, was obtained from the medicinal plant Isodon serra. The five rings in the mol­ecule exhibit the expected cis and trans junctions. The three six-membered rings adopt chair, twist-boat and boat conformations, while two five-membered rings adopt envelope conformations. There are two mol­ecules in the asymmetric unit, related by a non-crystallographic twofold screw axis; the main difference is in the different degrees of distortion of ring B. In the crystal, the mol­ecules are linked by inter­molecular O—H⋯O hydrogen bonds, forming chains along the b axis. International Union of Crystallography 2010-03-27 /pmc/articles/PMC2984011/ /pubmed/21580740 http://dx.doi.org/10.1107/S1600536810010573 Text en © Yan et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yan, Fu-Lin
Zhan, He-Qin
Feng, Chuang
Di, Xue-Mei
15α,20β-Dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene
title 15α,20β-Dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene
title_full 15α,20β-Dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene
title_fullStr 15α,20β-Dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene
title_full_unstemmed 15α,20β-Dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene
title_short 15α,20β-Dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene
title_sort 15α,20β-dihydr­oxy-6β-meth­oxy-6,7-seco-6,20-ep­oxy-1,7-olide-ent-kaur-16-ene
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984011/
https://www.ncbi.nlm.nih.gov/pubmed/21580740
http://dx.doi.org/10.1107/S1600536810010573
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AT fengchuang 15a20bdihydroxy6bmethoxy67seco620epoxy17olideentkaur16ene
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