Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

Biosensors are analytical devices being approachable for multiple analytes assay. Here, biosensors with intercepted acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) are presented as tool for assay of anticholinergic compounds such as pesticides, nerve agents and some natural toxins. Princ...

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Detalles Bibliográficos
Autor principal: Pohanka, Miroslav
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984101/
https://www.ncbi.nlm.nih.gov/pubmed/21217847
http://dx.doi.org/10.2478/v10102-009-0011-5
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author Pohanka, Miroslav
author_facet Pohanka, Miroslav
author_sort Pohanka, Miroslav
collection PubMed
description Biosensors are analytical devices being approachable for multiple analytes assay. Here, biosensors with intercepted acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) are presented as tool for assay of anticholinergic compounds such as pesticides, nerve agents and some natural toxins. Principle of assay is based on evaluation of cholinesterase activity and its pertinent decrease in presence of analyte. Nerve agents, pesticides, anticholinergic drugs useable for treatment of Alzheimer′s disease as well as myasthenia gravis and aflatoxins are enlisted as compounds simply analyzable by cholinesterase biosensors.
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spelling pubmed-29841012011-01-07 Cholinesterase based amperometric biosensors for assay of anticholinergic compounds Pohanka, Miroslav Interdiscip Toxicol Review Article Biosensors are analytical devices being approachable for multiple analytes assay. Here, biosensors with intercepted acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) are presented as tool for assay of anticholinergic compounds such as pesticides, nerve agents and some natural toxins. Principle of assay is based on evaluation of cholinesterase activity and its pertinent decrease in presence of analyte. Nerve agents, pesticides, anticholinergic drugs useable for treatment of Alzheimer′s disease as well as myasthenia gravis and aflatoxins are enlisted as compounds simply analyzable by cholinesterase biosensors. Slovak Toxicology Society SETOX 2009-06 2009-06 /pmc/articles/PMC2984101/ /pubmed/21217847 http://dx.doi.org/10.2478/v10102-009-0011-5 Text en Copyright©2009 Slovak Toxicology Society SETOX http://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Pohanka, Miroslav
Cholinesterase based amperometric biosensors for assay of anticholinergic compounds
title Cholinesterase based amperometric biosensors for assay of anticholinergic compounds
title_full Cholinesterase based amperometric biosensors for assay of anticholinergic compounds
title_fullStr Cholinesterase based amperometric biosensors for assay of anticholinergic compounds
title_full_unstemmed Cholinesterase based amperometric biosensors for assay of anticholinergic compounds
title_short Cholinesterase based amperometric biosensors for assay of anticholinergic compounds
title_sort cholinesterase based amperometric biosensors for assay of anticholinergic compounds
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984101/
https://www.ncbi.nlm.nih.gov/pubmed/21217847
http://dx.doi.org/10.2478/v10102-009-0011-5
work_keys_str_mv AT pohankamiroslav cholinesterasebasedamperometricbiosensorsforassayofanticholinergiccompounds

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