Cargando…

The effects of selected flavonoids on cytochromes P450 in rat liver and small intestine

In recent years, the consumption and use of dietary supplements containing concentrated phytochemicals (e.g. flavonoids) increased dramatically. Flavonoids, as foreign compounds (xenobiotics), have great potential to modulate the activity of cytochrome P450s (CYPs), xenobiotic-metabolizing enzymes i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Křížková, Jitka, Burdová, Kamila, Stiborová, Marie, Křen, Vladimír, Hodek, Petr
Formato:	Texto
Lenguaje:	English
Publicado:	Slovak Toxicology Society SETOX 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984105/ https://www.ncbi.nlm.nih.gov/pubmed/21217855 http://dx.doi.org/10.2478/v10102-009-0018-y

Ejemplares similares

Experimental approaches to evaluate activities of cytochromes P450 3A
por: Bořek-Dohalská, Lucie, et al.
Publicado: (2008)

Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 – similarity between human and rat enzymes
por: Svobodová, Martina, et al.
Publicado: (2008)

A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches
por: Stiborová, Marie, et al.
Publicado: (2015)

Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone
por: Mizerovská, Jana, et al.
Publicado: (2008)

Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro: experimental and theoretical approaches
por: Martínek, Václav, et al.
Publicado: (2017)

NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1
por: Stiborová, Marie, et al.
Publicado: (2016)

Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study
por: Stiborová, Marie, et al.
Publicado: (2009)

Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole
por: Naiman, Karel, et al.
Publicado: (2008)

Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
por: Stiborová, Marie, et al.
Publicado: (2017)

In Vitro Gender-Dependent Inhibition of Porcine Cytochrome P450 Activity by Selected Flavonoids and Phenolic Acids
por: Ekstrand, Bo, et al.
Publicado: (2015)

The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN™) Mice and Pure Enzymes
por: Stiborová, Marie, et al.
Publicado: (2014)

The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
por: Šulc, Miroslav, et al.
Publicado: (2016)

Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
por: Reed, Lindsay, et al.
Publicado: (2019)

Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2
por: Aimová, Dagmar, et al.
Publicado: (2008)

Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells
por: Hřebačková, Jana, et al.
Publicado: (2009)

Utilizing of Square Wave Voltammetry to Detect Flavonoids in the Presence of Human Urine
por: Adam, Vojtech, et al.
Publicado: (2007)

Inhibition of Cytochrome P450 Activities by Sophora flavescens Extract and Its Prenylated Flavonoids in Human Liver Microsomes
por: Yim, Daeun, et al.
Publicado: (2019)

Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice
por: Reed, Lindsay, et al.
Publicado: (2018)

Intestinal and Hepatic Expression of Cytochrome P450s and mdr1a in Rats with Indomethacin-Induced Small Intestinal Ulcers
por: Kawauchi, Shoji, et al.
Publicado: (2014)

Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver
por: Zhang, Hai-Feng, et al.
Publicado: (2016)

Intestinal cytochromes P450 regulating the intestinal microbiota and its probiotic profile
por: Bezirtzoglou, Eugenia Elefterios Venizelos
Publicado: (2012)

Distribution and induction of cytochrome P-450 in rat liver nuclear envelope
Publicado: (1981)

Cytochrome P450 in living donor liver transplantation
por: Chiu, King-Wah, et al.
Publicado: (2015)

Cytochrome b(5) plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine
por: Stiborová, Marie, et al.
Publicado: (2017)

Formation of DNA Adducts by Ellipticine and Its Micellar Form in Rats — A Comparative Study
por: Stiborova, Marie, et al.
Publicado: (2014)

NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
por: Stiborová, Marie, et al.
Publicado: (2016)

Correction to NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
por: Stiborová, Marie, et al.
Publicado: (2016)

An update on the role of intestinal cytochrome P450 enzymes in drug disposition
por: Xie, Fang, et al.
Publicado: (2016)

Effect of Cellgevity® Supplement on Selected Rat Liver Cytochrome P450 Enzyme Activity and Pharmacokinetic Parameters of Carbamazepine
por: Amponsah, Seth Kwabena, et al.
Publicado: (2020)

Spaceflight Effects on Cytochrome P450 Content in Mouse Liver
por: Moskaleva, Natalia, et al.
Publicado: (2015)

Inhibition of Cytochrome P450 by Propolis in Human Liver Microsomes
por: Ryu, Chang Seon, et al.
Publicado: (2016)

Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation
por: Indra, Radek, et al.
Publicado: (2019)

The Cytochrome P450 Homepage
por: Nelson, David R
Publicado: (2009)

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450
por: Campelo, Diana, et al.
Publicado: (2018)

Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes
por: Zhang, Zhi-Juan, et al.
Publicado: (2016)

Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine
por: Mrízová, Iveta, et al.
Publicado: (2016)

Cytochrome P‐450 Isozyme Pattern Is Related to Individual Susceptibility to Diethylnitrosamine‐induced Liver Cancer in Rats
por: Aitio, Antero, et al.
Publicado: (1991)

Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes
por: Mohos, Violetta, et al.
Publicado: (2020)

Overexpression of a Novel Cytochrome P450 Promotes Flavonoid Biosynthesis and Osmotic Stress Tolerance in Transgenic Arabidopsis
por: Ahmad, Naveed, et al.
Publicado: (2019)

Phylogenomic Analysis of Cytochrome P450 Gene Superfamily and Their Association with Flavonoids Biosynthesis in Peanut (Arachis hypogaea L.)
por: Zhang, Kun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_h1a2biv1racp2nor7qqav76n3f