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Neurobehavioral manifestations of developmental impairment of the brain

Individual characteristics of human nature (e.g. introversion, extroversion, mood, activity, adaptability, aggressiveness, social ability, anxiety) do not need to be primarily innate. They can be determined by the action of various influences and their interactions on functional development of the b...

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Detalles Bibliográficos
Autor principal: Dubovický, Michal
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984125/
https://www.ncbi.nlm.nih.gov/pubmed/21217874
http://dx.doi.org/10.2478/v10102-010-0012-4
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author Dubovický, Michal
author_facet Dubovický, Michal
author_sort Dubovický, Michal
collection PubMed
description Individual characteristics of human nature (e.g. introversion, extroversion, mood, activity, adaptability, aggressiveness, social ability, anxiety) do not need to be primarily innate. They can be determined by the action of various influences and their interactions on functional development of the brain. There is ample epidemiological and experimental evidence that chemical and/or physical factors acting during sensitive time windows of the brain development can cause mental, behavioral, emotional and/or cognitive disorders. Environmental pollutants, addictive substances, drugs, malnutrition, excessive stress and/or hypoxia-ischemia were reported to induce functional maldevelopment of the brain with consequent neurobehavioral disorders. The article provides review on most significant neurobehavioral manifestations of developmental impairment of the brain during prenatal, perinatal and early postnatal period. The most known adverse factors causing developmental neurobehavioral dysfunctions in humans as well as in experimental animals are discussed.
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spelling pubmed-29841252011-01-07 Neurobehavioral manifestations of developmental impairment of the brain Dubovický, Michal Interdiscip Toxicol Review Article Individual characteristics of human nature (e.g. introversion, extroversion, mood, activity, adaptability, aggressiveness, social ability, anxiety) do not need to be primarily innate. They can be determined by the action of various influences and their interactions on functional development of the brain. There is ample epidemiological and experimental evidence that chemical and/or physical factors acting during sensitive time windows of the brain development can cause mental, behavioral, emotional and/or cognitive disorders. Environmental pollutants, addictive substances, drugs, malnutrition, excessive stress and/or hypoxia-ischemia were reported to induce functional maldevelopment of the brain with consequent neurobehavioral disorders. The article provides review on most significant neurobehavioral manifestations of developmental impairment of the brain during prenatal, perinatal and early postnatal period. The most known adverse factors causing developmental neurobehavioral dysfunctions in humans as well as in experimental animals are discussed. Slovak Toxicology Society SETOX 2010-06 2010-06 /pmc/articles/PMC2984125/ /pubmed/21217874 http://dx.doi.org/10.2478/v10102-010-0012-4 Text en Copyright © 2010 Slovak Toxicology Society SETOX http://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Dubovický, Michal
Neurobehavioral manifestations of developmental impairment of the brain
title Neurobehavioral manifestations of developmental impairment of the brain
title_full Neurobehavioral manifestations of developmental impairment of the brain
title_fullStr Neurobehavioral manifestations of developmental impairment of the brain
title_full_unstemmed Neurobehavioral manifestations of developmental impairment of the brain
title_short Neurobehavioral manifestations of developmental impairment of the brain
title_sort neurobehavioral manifestations of developmental impairment of the brain
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984125/
https://www.ncbi.nlm.nih.gov/pubmed/21217874
http://dx.doi.org/10.2478/v10102-010-0012-4
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