Preclinical electrogastrography in experimental pigs

Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric activity or slow waves from cutaneous leads placed over the stomach. This paper provides a comprehensive review of preclinical EGG. Our group recently set up and worked out the methods for EGG in experimental...

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Detalles Bibliográficos
Autores principales: Květina, Jaroslav, Varayil, Jithinraj Edakkanambeth, Ali, Shahzad Marghoob, Kuneš, Martin, Bureš, Jan, Tachecí, Ilja, Rejchrt, Stanislav, Kopáčová, Marcela
Formato: Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984130/
https://www.ncbi.nlm.nih.gov/pubmed/21217873
http://dx.doi.org/10.2478/v10102-010-0011-5
Descripción
Sumario:Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric activity or slow waves from cutaneous leads placed over the stomach. This paper provides a comprehensive review of preclinical EGG. Our group recently set up and worked out the methods for EGG in experimental pigs. We gained our initial experience in the use of EGG in assessment of porcine gastric myoelectric activity after volume challenge and after intragastric administration of itopride and erythromycin. The mean dominant frequency in pigs is comparable with that found in humans. EGG in experimental pigs is feasible. Experimental EGG is an important basis for further preclinical projects in pharmacology and toxicology.

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