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Defensin alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients
BACKGROUND: It is known that alpha-defensin expression is enhanced in colon cancer. However, the expression of human alpha defensin 6 (DEFA 6) in earlier stages, such as adenoma, has so far not yet been studied in a patient resolved manner. METHODS: By using quantitative Real Time-PCR, the gene expr...
Autores principales: | Radeva, Mariya Y, Jahns, Franziska, Wilhelm, Anne, Glei, Michael, Settmacher, Utz, Greulich, Karl Otto, Mothes, Henning |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984430/ https://www.ncbi.nlm.nih.gov/pubmed/20979654 http://dx.doi.org/10.1186/1471-2407-10-588 |
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