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Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies

Recently genome-wide association studies (GWAS) have identified numerous susceptibility variants for complex diseases. In this study we proposed several approaches to estimate the total number of variants underlying these diseases. We assume that the variance explained by genetic markers (Vg) follow...

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Detalles Bibliográficos
Autores principales:	So, Hon-Cheong, Yip, Benjamin H. K., Sham, Pak Chung
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984437/ https://www.ncbi.nlm.nih.gov/pubmed/21103334 http://dx.doi.org/10.1371/journal.pone.0013898

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