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Dynamic, Large-Scale Profiling of Transcription Factor Activity from Live Cells in 3D Culture

BACKGROUND: Extracellular activation of signal transduction pathways and their downstream target transcription factors (TFs) are critical regulators of cellular processes and tissue development. The intracellular signaling network is complex, and techniques that quantify the activities of numerous p...

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Detalles Bibliográficos
Autores principales: Weiss, Michael S., Peñalver Bernabé, Beatriz, Bellis, Abigail D., Broadbelt, Linda J., Jeruss, Jacqueline S., Shea, Lonnie D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984444/
https://www.ncbi.nlm.nih.gov/pubmed/21103341
http://dx.doi.org/10.1371/journal.pone.0014026