HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression

BACKGROUND: 17α-Ethynyl-5-androsten-3β, 7β, 17β-triol (HE3286) is a synthetic derivative of an endogenous steroid androstenetriol (β-AET), a metabolite of the abundant adrenal steroid deyhdroepiandrosterone (DHEA), with broad anti-inflammatory activities. We tested the ability of this novel syntheti...

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Detalles Bibliográficos
Autores principales: Conrad, Douglas, Wang, Angela, Pieters , Raymond, Nicoletti, Ferdinando, Mangano, Katia, van Heeckeren, Anna M, White, Steven K, Frincke, James M, Reading, Christopher L, Stickney, Dwight, Auci, Dominick L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984480/
https://www.ncbi.nlm.nih.gov/pubmed/21034489
http://dx.doi.org/10.1186/1476-9255-7-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984480/
https://www.ncbi.nlm.nih.gov/pubmed/21034489
http://dx.doi.org/10.1186/1476-9255-7-52

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