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HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression

BACKGROUND: 17α-Ethynyl-5-androsten-3β, 7β, 17β-triol (HE3286) is a synthetic derivative of an endogenous steroid androstenetriol (β-AET), a metabolite of the abundant adrenal steroid deyhdroepiandrosterone (DHEA), with broad anti-inflammatory activities. We tested the ability of this novel syntheti...

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Detalles Bibliográficos
Autores principales:	Conrad, Douglas, Wang, Angela, Pieters , Raymond, Nicoletti, Ferdinando, Mangano, Katia, van Heeckeren, Anna M, White, Steven K, Frincke, James M, Reading, Christopher L, Stickney, Dwight, Auci, Dominick L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984480/ https://www.ncbi.nlm.nih.gov/pubmed/21034489 http://dx.doi.org/10.1186/1476-9255-7-52

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