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Peripheral nerve injury and TRPV1-expressing primary afferent C-fibers cause opening of the blood-brain barrier
BACKGROUND: The blood-brain barrier (BBB) plays the crucial role of limiting exposure of the central nervous system (CNS) to damaging molecules and cells. Dysfunction of the BBB is critical in a broad range of CNS disorders including neurodegeneration, inflammatory or traumatic injury to the CNS, an...
Autores principales: | Beggs, Simon, Liu, Xue Jun, Kwan, Chun, Salter, Michael W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984489/ https://www.ncbi.nlm.nih.gov/pubmed/21044346 http://dx.doi.org/10.1186/1744-8069-6-74 |
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