Cargando…

Ethylene Glycol Monomethyl Ether–Induced Toxicity Is Mediated through the Inhibition of Flavoprotein Dehydrogenase Enzyme Family

Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order to gain mechanistic understanding of EGME-indu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takei, Makoto, Ando, Yosuke, Saitoh, Wataru, Tanimoto, Tomoe, Kiyosawa, Naoki, Manabe, Sunao, Sanbuissho, Atsushi, Okazaki, Osamu, Iwabuchi, Haruo, Yamoto, Takashi, Adam, Klaus-Peter, Weiel, James E., Ryals, John A., Milburn, Michael V., Guo, Lining
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Reproductive and Developmental Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984528/ https://www.ncbi.nlm.nih.gov/pubmed/20616209 http://dx.doi.org/10.1093/toxsci/kfq211

Ejemplares similares

Practical Application of Toxicogenomics for Profiling Toxicant-Induced Biological Perturbations
por: Kiyosawa, Naoki, et al.
Publicado: (2010)

Ethylene glycol monomethyl ether and propylene glycol monomethyl ether: metabolism, disposition, and subchronic inhalation toxicity studies.
por: Miller, R R, et al.
Publicado: (1984)

Reproductive toxicology. Ethylene glycol monomethyl ether.
Publicado: (1997)

Reproductive toxicology. Ethylene glycol monomethyl ether.
Publicado: (1997)

Reproductive toxicology. Ethylene glycol monomethyl ether.
Publicado: (1997)

Reproductive toxicology. Ethylene glycol monomethyl ether.
Publicado: (1997)

Reproductive toxicology. Propylene glycol monomethyl ether.
Publicado: (1997)

Ethylene glycol monomethyl ether (EGME) and propylene glycol monomethyl ether (PGME): inhalation fertility and teratogenicity studies in rats, mice and rabbits.
por: Hanley, T R, et al.
Publicado: (1984)

Behavioral teratology of ethylene glycol monomethyl and monoethyl ethers.
por: Nelson, B K, et al.
Publicado: (1984)

Toxicogenomic Biomarkers for Liver Toxicity
por: Kiyosawa, Naoki, et al.
Publicado: (2009)

From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects
por: Balmer, Nina V., et al.
Publicado: (2014)

Disruption of paired-associate learning in rat offspring perinatally exposed to dioxins
por: Kakeyama, Masaki, et al.
Publicado: (2013)

Programming of metabolic effects in C57BL/6JxFVB mice by in utero and lactational exposure to perfluorooctanoic acid
por: van Esterik, J. C. J., et al.
Publicado: (2015)

Extended evaluation on the ES-D3 cell differentiation assay combined with the BeWo transport model, to predict relative developmental toxicity of triazole compounds
por: Li, Hequn, et al.
Publicado: (2015)

High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes
por: Reif, David M., et al.
Publicado: (2015)

Investigations on the dose–response relationship of combined exposure to low doses of three anti-androgens in Wistar rats
por: Schneider, Steffen, et al.
Publicado: (2017)

Head skeleton malformations in zebrafish (Danio rerio) to assess adverse effects of mixtures of compounds
por: Staal, Yvonne C. M., et al.
Publicado: (2018)

Shedding new light on early sex determination in zebrafish
por: King, Alex C., et al.
Publicado: (2020)

Acute, reproductive, and developmental toxicity of essential oils assessed with alternative in vitro and in vivo systems
por: Lanzerstorfer, Peter, et al.
Publicado: (2020)

A model-based approach to designing developmental toxicology experiments using sea urchin embryos
por: Collins, Michael D., et al.
Publicado: (2022)

Effects of the food colorant carmoisine on zebrafish embryos at a wide range of concentrations
por: Kiziltan, Tuba, et al.
Publicado: (2022)

Grouping of chemicals into mode of action classes by automated effect pattern analysis using the zebrafish embryo toxicity test
por: Teixidó, E., et al.
Publicado: (2022)

Predictive assays for craniofacial malformations: evaluation in Xenopus laevis embryos exposed to triadimefon
por: Battistoni, Maria, et al.
Publicado: (2022)

Mapping DEHP to the adverse outcome pathway network for human female reproductive toxicity
por: Pogrmic-Majkic, Kristina, et al.
Publicado: (2022)

Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole
por: Kugathas, Indusha, et al.
Publicado: (2023)

Mono(2-ethylhexyl) phthalate induces transcriptomic changes in placental cells based on concentration, fetal sex, and trophoblast cell type
por: Lapehn, Samantha, et al.
Publicado: (2023)

Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture
por: Metruccio, Francesca, et al.
Publicado: (2022)

Reproductive toxicology. Ethylene glycol monomethyl ether: litter five.
Publicado: (1997)

Reproductive toxicology. Ethylene glycol monomethyl ether: litter two.
Publicado: (1997)

Testicular toxicity produced by ethylene glycol monomethyl and monoethyl ethers in the rat.
por: Foster, P M, et al.
Publicado: (1984)

Altered hepatic cytochrome P450 expression in cats after chronic exposure to decabromodiphenyl ether (BDE-209)
por: KHIDKHAN, Kraisiri, et al.
Publicado: (2020)

Gene expression profiling after exposure to a chemical carcinogen, Pentabrominated Diphenyl Ether, at different life stages
por: Shockley, Keith R., et al.
Publicado: (2023)

Rapeseed Oil Monoester of Ethylene Glycol Monomethyl Ether as a New Biodiesel
por: Dayong, Jiang, et al.
Publicado: (2011)

Effects of ethylene glycol monomethyl ether on various parameters of testicular function in the F344 rat.
por: Chapin, R E, et al.
Publicado: (1984)

Human Primordial Germ Cell Formation Is Diminished by Exposure to Environmental Toxicants Acting through the AHR Signaling Pathway
por: Kee, Kehkooi, et al.
Publicado: (2010)

Toxicant-Induced Leakage of Germ Cell–Specific Proteins from Seminiferous Tubules in the Rat: Relationship to Blood-Testis Barrier Integrity and Prospects for Biomonitoring
por: Elkin, Naomi D., et al.
Publicado: (2010)

Phthalates Impair Germ Cell Number in the Mouse Fetal Testis by an Androgen- and Estrogen-Independent Mechanism
por: Lehraiki, Abdelali, et al.
Publicado: (2009)

Effects of Chronic Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants on the Reproductive and Thyroid System in Adult Male Rats
por: Ernest, Sheila R., et al.
Publicado: (2012)

The Activation of DNA Damage Detection and Repair Responses in Cleavage-Stage Rat Embryos by a Damaged Paternal Genome
por: Grenier, Lisanne, et al.
Publicado: (2012)

Teratogen-Induced Oxidative Stress Targets Glyceraldehyde-3-Phosphate Dehydrogenase in the Organogenesis Stage Mouse Embryo
por: Schlisser, Ava E., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_khh0q3drosujdpv9ijt36g5c9i