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Teratogen-Induced Oxidative Stress Targets Glyceraldehyde-3-Phosphate Dehydrogenase in the Organogenesis Stage Mouse Embryo

Exposure during the organogenesis stage of the mouse embryo to the model teratogen, hydroxyurea (HU), induces curly tail and limb malformations. Oxidative stress contributes to the developmental toxicity of HU. Reactive oxygen species (ROS) interact with polyunsaturated bilipid membranes to form α,β...

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Detalles Bibliográficos
Autores principales:	Schlisser, Ava E., Yan, Jin, Hales, Barbara F.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Reproductive and Developmental Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984529/ https://www.ncbi.nlm.nih.gov/pubmed/20889679 http://dx.doi.org/10.1093/toxsci/kfq287

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