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How pharmacokinetic and pharmacodynamic principles pave the way for optimal basal insulin therapy in type 2 diabetes

This pedagogical review illustrates the differences between pharmacokinetic (PK) and pharmacodynamic (PD) measures, using insulin therapy as the primary example. The main conclusion is that PD parameters are of greater clinical significance for insulin therapy than PK parameters. The glucose-clamp t...

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Detalles Bibliográficos
Autores principales: Arnolds, S, Kuglin, B, Kapitza, C, Heise, T
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984539/
https://www.ncbi.nlm.nih.gov/pubmed/20618882
http://dx.doi.org/10.1111/j.1742-1241.2010.02470.x