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Investigation and improvement of DNA cleavage models of polyamide + Cu(II) nuclease + OOH(- )ligands bound to DNA

BACKGROUND: Copper nucleases as a famous class of artificial metallonucleases have attracted considerable interest in relation to their diverse potentials not only as therapeutic agents but also in genomic researches. Copper nucleases present high efficient oxidative cleavage of DNA, in which DNA st...

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Detalles Bibliográficos
Autores principales: Yue, Hongwei, Zhu, Yanyan, Wang, Yan, Chen, Guangju
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984560/
https://www.ncbi.nlm.nih.gov/pubmed/20950488
http://dx.doi.org/10.1186/1472-6807-10-35

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