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Investigation and improvement of DNA cleavage models of polyamide + Cu(II) nuclease + OOH(- )ligands bound to DNA
BACKGROUND: Copper nucleases as a famous class of artificial metallonucleases have attracted considerable interest in relation to their diverse potentials not only as therapeutic agents but also in genomic researches. Copper nucleases present high efficient oxidative cleavage of DNA, in which DNA st...
Autores principales: | Yue, Hongwei, Zhu, Yanyan, Wang, Yan, Chen, Guangju |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984560/ https://www.ncbi.nlm.nih.gov/pubmed/20950488 http://dx.doi.org/10.1186/1472-6807-10-35 |
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