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Optimizing structural modeling for a specific protein scaffold: knottins or inhibitor cystine knots
BACKGROUND: Knottins are small, diverse and stable proteins with important drug design potential. They can be classified in 30 families which cover a wide range of sequences (1621 sequenced), three-dimensional structures (155 solved) and functions (> 10). Inter knottin similarity lies mainly betw...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984590/ https://www.ncbi.nlm.nih.gov/pubmed/21029427 http://dx.doi.org/10.1186/1471-2105-11-535 |