Intron 4 Containing Novel GABAB1 Isoforms Impair GABAB Receptor Function

BACKGROUND: Gamma-aminobutyric acid type B (GABAB) receptors decrease neural activity through G protein signaling. There are two subunits, GABAB1 and GABAB2. Alternative splicing provides GABAB1 with structural and functional diversity. cDNA microarrays showed strong signals from human brain RNA usi...

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Detalles Bibliográficos
Autores principales: Lee, Changhoon, Mayfield, R. Dayne, Harris, R. Adron
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987798/
https://www.ncbi.nlm.nih.gov/pubmed/21124972
http://dx.doi.org/10.1371/journal.pone.0014044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987798/
https://www.ncbi.nlm.nih.gov/pubmed/21124972
http://dx.doi.org/10.1371/journal.pone.0014044

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