Cargando…

Modelling the Evolution and Spread of HIV Immune Escape Mutants

During infection with human immunodeficiency virus (HIV), immune pressure from cytotoxic T-lymphocytes (CTLs) selects for viral mutants that confer escape from CTL recognition. These escape variants can be transmitted between individuals where, depending upon their cost to viral fitness and the CTL...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fryer, Helen R., Frater, John, Duda, Anna, Roberts, Mick G., Phillips, Rodney E., McLean, Angela R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987822/ https://www.ncbi.nlm.nih.gov/pubmed/21124991 http://dx.doi.org/10.1371/journal.ppat.1001196

Ejemplares similares

Modelling the Spread of HIV Immune Escape Mutants in a Vaccinated Population
por: Fryer, Helen R., et al.
Publicado: (2011)

Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes
por: Palmer, Duncan, et al.
Publicado: (2013)

Structured Observations Reveal Slow HIV-1 CTL Escape
por: Roberts, Hannah E., et al.
Publicado: (2015)

No evidence for competition between cytotoxic T-lymphocyte responses in HIV-1 infection
por: Fryer, Helen R., et al.
Publicado: (2009)

Increased T cell trafficking as adjunct therapy for HIV-1
por: Fryer, Helen R., et al.
Publicado: (2018)

The impact of antiretroviral therapy on population-level virulence evolution of HIV-1
por: Roberts, Hannah E., et al.
Publicado: (2015)

There Is No Safe Dose of Prions
por: Fryer, Helen R., et al.
Publicado: (2011)

Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution
por: Venkatesan, S, et al.
Publicado: (2018)

Mapping the drivers of within-host pathogen evolution using massive data sets
por: Palmer, Duncan S., et al.
Publicado: (2019)

Within-Host Stochastic Emergence Dynamics of Immune-Escape Mutants
por: Hartfield, Matthew, et al.
Publicado: (2015)

HIV-1 mutants that escape the cytotoxic T-lymphocytes are defective in viral DNA integration
por: Balasubramaniam, Muthukumar, et al.
Publicado: (2022)

Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-1
por: Zhang, Yu, et al.
Publicado: (2020)

Allosteric mutants show that PrfA activation is dispensable for vacuole escape but required for efficient spread and Listeria survival in vivo
por: Deshayes, Caroline, et al.
Publicado: (2012)

Sequential Emergence and Wide Spread of Neutralization Escape Middle East Respiratory Syndrome Coronavirus Mutants, South Korea, 2015
por: Kim, Yeon-Sook, et al.
Publicado: (2019)

Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction
por: Xie, Maorong, et al.
Publicado: (2019)

Dynamics of Immune Escape during HIV/SIV Infection
por: Althaus, Christian L., et al.
Publicado: (2008)

Initiation and spread of escape waves within animal groups
por: Herbert-Read, James E., et al.
Publicado: (2015)

Hepatitis B virus S gene escape mutants
por: Purdy, Michael A.
Publicado: (2007)

Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants
por: English, Suzanne, et al.
Publicado: (2011)

Vaccination strategies when vaccines are scarce: on conflicts between reducing the burden and avoiding the evolution of escape mutants
por: Geoffroy, Félix, et al.
Publicado: (2022)

HIV switches to escape
por: Bashyam, Hema
Publicado: (2008)

Editorial: Immune Surveillance of the HIV Reservoir: Mechanisms, Therapeutic Targeting and New Avenues for HIV Cure
por: Prado, Julia G., et al.
Publicado: (2020)

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
por: McGranahan, Nicholas, et al.
Publicado: (2017)

SARS-CoV-2 Evolution and Immune Escape in Immunocompromised Patients
por: Scherer, Erin M., et al.
Publicado: (2022)

Application of magnetic field hyperthermia and superparamagnetic iron oxide nanoparticles to HIV-1-specific T-cell cytotoxicity
por: Williams, James P, et al.
Publicado: (2013)

Influence of immune escape and nasopharyngeal virus load on the spread of SARS-CoV-2 Omicron variant
por: Migueres, Marion, et al.
Publicado: (2022)

Severe acute respiratory syndrome coronavirus 2 escape mutants and protective immunity from natural infections or immunizations
por: Di Caro, Antonino, et al.
Publicado: (2021)

Mutant p53 gain of function mediates cancer immune escape that is counteracted by APR-246
por: Zhou, Xiaolei, et al.
Publicado: (2022)

Insights into the Evolution and Emergence of a Novel Infectious Disease
por: Kubiak, Ruben J., et al.
Publicado: (2010)

Immune landscape in vulvar cancer-draining lymph nodes indicates distinct immune escape mechanisms in support of metastatic spread and growth
por: Heeren, Anne Marijne, et al.
Publicado: (2021)

Jigsaw puzzle of SARS-CoV-2 RBD evolution and immune escape
por: Yi, Chunyan, et al.
Publicado: (2022)

The Route of HIV Escape from Immune Response Targeting Multiple Sites Is Determined by the Cost-Benefit Tradeoff of Escape Mutations
por: Batorsky, Rebecca, et al.
Publicado: (2014)

Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency
por: Hurst, Tara, et al.
Publicado: (2016)

The Cat and Mouse of HIV-1 Antibody Escape
por: Mascola, John R.
Publicado: (2009)

Targets of Immune Escape Mechanisms in Cancer: Basis for Development and Evolution of Cancer Immune Checkpoint Inhibitors
por: Dutta, Shovan, et al.
Publicado: (2023)

Immune escape mutations in HIV-1 controllers in the Brazilian Amazon region
por: Gomes, Samara Tatielle Monteiro, et al.
Publicado: (2020)

Immune Pressure on Polymorphous Influenza B Populations Results in Diverse Hemagglutinin Escape Mutants and Lineage Switching
por: Plant, Ewan P., et al.
Publicado: (2020)

The Correlation Between SPP1 and Immune Escape of EGFR Mutant Lung Adenocarcinoma Was Explored by Bioinformatics Analysis
por: Zheng, Yi, et al.
Publicado: (2021)

T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics
por: Akahoshi, Tomohiro, et al.
Publicado: (2020)

Convergent Evolution of Escape from Hepaciviral Antagonism in Primates
por: Patel, Maulik R., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9o7c6rajkso9tl2tea1tbgo3tj