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Using Sequence-Specific Chemical and Structural Properties of DNA to Predict Transcription Factor Binding Sites
An important step in understanding gene regulation is to identify the DNA binding sites recognized by each transcription factor (TF). Conventional approaches to prediction of TF binding sites involve the definition of consensus sequences or position-specific weight matrices and rely on statistical a...
Autores principales: | Bauer, Amy L., Hlavacek, William S., Unkefer, Pat J., Mu, Fangping |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987836/ https://www.ncbi.nlm.nih.gov/pubmed/21124945 http://dx.doi.org/10.1371/journal.pcbi.1001007 |
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